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Mechanisms underlying the pathogenesis of arthritogenic alphaviruses: host immune responses and virus persistence.

作者信息

Hawman David W, Burrack Kristina S, Morrison Thomas E

机构信息

Department of Microbiology, University of Colorado School of Medicine, 12800 East 19th Avenue, Mail Stop 8333, Aurora, CO 80045, USA.

出版信息

Future Virol. 2019;9(5):441-444. doi: 10.2217/fvl.14.27. Epub 2014 Jun 16.

DOI:10.2217/fvl.14.27
PMID:33907560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8074857/
Abstract
摘要

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PLoS Negl Trop Dis. 2014 Feb 20;8(2):e2719. doi: 10.1371/journal.pntd.0002719. eCollection 2014 Feb.
2
Correlation of plasma viral loads and presence of Chikungunya IgM antibodies with cytokine/chemokine levels during acute Chikungunya virus infection.在急性基孔肯雅病毒感染期间,血浆病毒载量和基孔肯雅 IgM 抗体的存在与细胞因子/趋化因子水平的相关性。
J Med Virol. 2014 Aug;86(8):1393-401. doi: 10.1002/jmv.23875. Epub 2014 Feb 13.
3
Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune response.持续性基孔肯雅病毒感染引起的慢性关节疾病受适应性免疫反应的控制。
J Virol. 2013 Dec;87(24):13878-88. doi: 10.1128/JVI.02666-13. Epub 2013 Oct 16.
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Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity.基孔肯雅病毒感染会导致老年恒河猴的抗病毒免疫缺陷,从而导致更高和持续的病毒复制。
PLoS Negl Trop Dis. 2013 Jul 25;7(7):e2343. doi: 10.1371/journal.pntd.0002343. Print 2013.
5
Chikungunya virus-associated long-term arthralgia: a 36-month prospective longitudinal study.基孔肯雅热相关的长期关节痛:一项 36 个月的前瞻性纵向研究。
PLoS Negl Trop Dis. 2013;7(3):e2137. doi: 10.1371/journal.pntd.0002137. Epub 2013 Mar 21.
6
The problem of choice: current biologic agents and future prospects in RA.选择的问题:类风湿关节炎的当前生物制剂和未来前景。
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Nat Rev Rheumatol. 2012 May 8;8(7):420-9. doi: 10.1038/nrrheum.2012.64.