唐氏综合征患者的新冠肺炎肺炎：约2例。
COVID 19 pneumonia in Down syndrome patients: About 2 cases.
作者信息
El Kaouini Abderrahim, El Rhalete Abdelilah, Aabdi Mohammed, Azizi Mohammed, Maarad Mohammed, Bahouh Choukri, Bkiyer Houssam, Housni Brahim
机构信息
Intensive Care Unit and and Anesthesiology Department, Mohammed VI University Hospital, Oujda, Morocco.
出版信息
Ann Med Surg (Lond). 2021 May;65:102324. doi: 10.1016/j.amsu.2021.102324. Epub 2021 Apr 22.
INTRODUCTION
Covid-19 is a severe emerging infection with high rate of mortality. Patients with Covid-19 and Down syndrome represent a high rate of morbidity and mortality.
CASE PRESENTATION
Case 1: A 27-year-old white male with Down's syndrome admitted to the ICU for Covid-19 infection with lung damage of 30-50%. The patient improved and referred to the pulmonology department.Case 2: A 49-year-old man admitted to the ICU for Covid-19 infection with a lung damage of 50%. The evolution was lethal and he passed away after 12 days of his admission.
CONCLUSION
People suffering from Down syndrome should be given priority in the management of acute respiratory distress following infection with SARS COV2, or even candidates for early immunosuppressive treatment and possible vaccination once started.
引言
新冠病毒病（Covid-19）是一种严重的新发感染病，死亡率很高。患有新冠病毒病和唐氏综合征的患者发病率和死亡率都很高。
病例报告
病例1：一名27岁患有唐氏综合征的白人男性因新冠病毒病感染入住重症监护病房，肺部损伤达30%-50%。患者病情好转后转诊至肺病科。病例2：一名49岁男性因新冠病毒病感染入住重症监护病房，肺部损伤达50%。病情发展导致死亡，入院12天后去世。
结论
唐氏综合征患者在感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）后发生急性呼吸窘迫时应优先得到治疗，甚至一旦开始可考虑作为早期免疫抑制治疗和可能接种疫苗的对象。
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