Foglia Ralph, Kline Anna, Cooperman Nina A
Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, 317 George Street, Suite 105, New Brunswick, NJ 08901 USA.
Curr Addict Rep. 2021;8(2):319-329. doi: 10.1007/s40429-021-00368-6. Epub 2021 Apr 22.
The purpose of this review is to provide a review of the current literature surrounding opioid overdose risk factors, focusing on relatively new factors in the opioid crisis.
Both a market supply driving force and a subpopulation of people who use opioids actively seeking out fentanyl are contributing to its recent proliferation in the opioid market. Harm reduction techniques such as fentanyl testing strips, naloxone education and distribution, drug sampling behaviors, and supervised injection facilities are all seeing expanded use with increasing amounts of research being published regarding their effectiveness. Availability and use of interventions such as medication for opioid use disorder and peer recovery coaching programs are also on the rise to prevent opioid overdose.
The opioid epidemic is an evolving crisis, necessitating continuing research to identify novel overdose risk factors and the development of new interventions targeting at-risk populations.
本综述旨在对当前围绕阿片类药物过量风险因素的文献进行综述,重点关注阿片类药物危机中的相对新出现的因素。
市场供应驱动力以及积极寻求芬太尼的阿片类药物使用者亚群体,都促使芬太尼最近在阿片类药物市场上扩散。诸如芬太尼检测试纸、纳洛酮教育与分发、药物采样行为以及监督注射设施等减少伤害技术,随着关于其有效性的研究不断发表,其使用范围都在扩大。用于阿片类药物使用障碍的药物等干预措施的可及性和使用,以及同伴康复指导项目也在增加,以预防阿片类药物过量。
阿片类药物流行是一场不断演变的危机,需要持续开展研究以识别新的过量风险因素,并开发针对高危人群的新干预措施。