Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
School of Sport and Exercise, University of Gloucestershire, Gloucester, UK.
Psychophysiology. 2021 Aug;58(8):e13830. doi: 10.1111/psyp.13830. Epub 2021 Apr 28.
Acute prolonged sitting leads to cerebrovascular disruptions. However, it is unclear how prolonged sitting interacts with other common behaviors, including high- (HGI) and low-glycemic index (LGI) meals. Using a double-blind randomized cross-over design, this study evaluated the effects of prolonged (3 hr) sitting, with a high- (HGI; GI: 100) or low-glycemic index (LGI; GI: 19) meal on total brain blood flow (Q ) and executive function. Eighteen young, healthy, active participants (22.6 [3.1] y, 33% F, 24.3 [3.7] kg/m ) sat for 3 hr after consuming an HGI or LGI meal. Using Doppler ultrasound to measure internal carotid (ICA) and vertebral (VA) artery blood flow, Q was calculated: (ICA blood flow + VA blood flow) × 2. Executive function was assessed using the Stroop Test and Trail Making Test-Part B. Brain fog was measured using a modified Borg Category Scale with Ratio properties (CR10). Following 3 hr of sitting, there was a significant decrease in Q with time (p = .001, ES = -0.26), though there were nonsignificant interaction (p = .216) and condition effects (p = .174). Brain fog increased (p = .024, ES = 0.27) and Stroop reaction time worsened with time (p = .001, ES: -0.40), though there were nonsignificant condition effects for brain fog (p = .612) and the Stroop test (p = .445). There was a nonsignificant condition effect (p = .729) for the Trail Making Test-Part B, but completion time improved with time (p = .001, ES = -0.40). In conclusion, 3 hr of prolonged sitting decreases Q and executive function independent of glycemic index in young, healthy adults.
急性长时间久坐会导致脑血管破裂。然而，目前尚不清楚长时间久坐与其他常见行为（包括高（HGI）和低升糖指数（LGI）膳食）之间如何相互作用。本研究采用双盲随机交叉设计，评估了长时间（3 小时）坐姿、高（HGI；血糖指数：100）或低升糖指数（LGI；血糖指数：19）膳食对总脑血流量（Q）和执行功能的影响。18 名年轻、健康、活跃的参与者（22.6 [3.1] 岁，33% 为女性，24.3 [3.7] kg/m ）在食用 HGI 或 LGI 膳食后静坐 3 小时。使用多普勒超声测量颈内动脉（ICA）和椎动脉（VA）的血流，计算 Q：（ICA 血流+VA 血流）×2。采用 Stroop 测试和 Trail Making Test-Part B 评估执行功能。采用改良 Borg 比例量表（CR10）评估脑雾。静坐 3 小时后，Q 随时间显著下降（p =.001，ES = -0.26），但无交互作用（p =.216）和条件效应（p =.174）。脑雾随时间增加（p =.024，ES = 0.27），Stroop 反应时间恶化（p =.001，ES：-0.40），但脑雾（p =.612）和 Stroop 测试（p =.445）的条件效应无统计学意义。Trail Making Test-Part B 的条件效应无统计学意义（p =.729），但完成时间随时间改善（p =.001，ES = -0.40）。总之，3 小时的长时间久坐会降低年轻健康成年人的 Q 和执行功能，而与血糖指数无关。
