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1
Should adjuvant chemotherapy be formally studied among patients found to have pelvic lymph node metastases following radical hysterectomy with lymphadenectomy for early-stage cervical cancer?对于早期宫颈癌行根治性子宫切除术及淋巴结清扫术后发现盆腔淋巴结转移的患者，是否应正式开展辅助化疗的研究？
J Gynecol Oncol. 2021 Jul;32(4):e62. doi: 10.3802/jgo.2021.32.e62. Epub 2021 Apr 19.
2
Risk factors of pelvic lymph node metastasis in cervical adenocarcinoma following radical hysterectomy and pelvic lymphadenectomy.根治性子宫切除术和盆腔淋巴结清扫术后宫颈腺癌盆腔淋巴结转移的危险因素
J Med Assoc Thai. 2014 Nov;97 Suppl 11:S87-95.
3
Radical hysterectomy with or without para-aortic lymphadenectomy for patients with stage IB2, IIA2, and IIB cervical cancer: outcomes for a series of 308 patients.IB2、IIA2和IIB期宫颈癌患者行根治性子宫切除术加或不加主动脉旁淋巴结清扫术：308例患者的治疗结果
Int J Clin Oncol. 2016 Apr;21(2):359-366. doi: 10.1007/s10147-015-0907-3. Epub 2015 Oct 5.
4
Comparison of survival outcomes with or without Para-aortic lymphadenectomy in surgical patients with stage IB1-IIA2 cervical cancer in China from 2004 to 2016.比较 2004 年至 2016 年中国 IB1-IIA2 期宫颈癌手术患者行或不行Para-aortic lymphadenectomy 的生存结局。
BMC Cancer. 2021 Oct 9;21(1):1091. doi: 10.1186/s12885-021-08797-2.
5
Radical hysterectomy and pelvic lymphadenectomy for stage IB2 cervical cancer.针对IB2期宫颈癌的根治性子宫切除术和盆腔淋巴结清扫术。
Gynecol Oncol. 2004 May;93(2):429-34. doi: 10.1016/j.ygyno.2004.01.038.
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The case for completing the lymphadenectomy when positive lymph nodes are found during radical hysterectomy for cervical carcinoma.在宫颈癌根治性子宫切除术中发现阳性淋巴结时完成淋巴结清扫术的理由。
Acta Obstet Gynecol Scand. 2000 Jan;79(1):72-6.
7
Sentinel node detection in cervical cancer with (99m)Tc-phytate.利用（99m）锝-植酸盐检测宫颈癌前哨淋巴结
Gynecol Oncol. 2005 May;97(2):588-95. doi: 10.1016/j.ygyno.2005.02.014.
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Topographic distribution of lymph node metastasis in patients with stage IB1 cervical cancer: an analysis of 8314 lymph nodes.IB1 期宫颈癌患者淋巴结转移的分布：8314 枚淋巴结的分析。
Radiat Oncol. 2021 Mar 20;16(1):54. doi: 10.1186/s13014-021-01781-x.
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Sentinel node detection with (99m)Tc phytate alone is satisfactory for cervical cancer patients undergoing radical hysterectomy and pelvic lymphadenectomy.单独使用 (99m)Tc 植酸钠进行前哨淋巴结检测，对接受根治性子宫切除术和盆腔淋巴结切除术的宫颈癌患者是令人满意的。
Int J Clin Oncol. 2010 Feb;15(1):52-8. doi: 10.1007/s10147-009-0010-8. Epub 2010 Jan 21.
10
Extent of disease as an indication for pelvic radiation following radical hysterectomy and bilateral pelvic lymph node dissection in the treatment of stage IB and IIA cervical carcinoma.在治疗IB期和IIA期宫颈癌时，根治性子宫切除术后盆腔放疗的指征——疾病范围及双侧盆腔淋巴结清扫情况
Gynecol Oncol. 1994 Jul;54(1):4-9. doi: 10.1006/gyno.1994.1157.

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1
ASO Author Reflections: Tackling the Unresolved Topic: Impact of Adjuvant Chemotherapy on Survival in Patients with Surgically Treated Uterine Cervical Cancer.美国骨科学会作者反思：攻克未解决的话题——辅助化疗对手术治疗子宫颈癌患者生存率的影响
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Adjuvant Chemotherapy versus Concurrent Chemoradiotherapy for Surgically Treated T1b Uterine Cervical Cancer: A Propensity Score Matched Analysis of the JSOG Nationwide Data.辅助化疗与同步放化疗治疗手术切除的T1b期子宫颈癌：基于日本妇产科肿瘤学会全国数据的倾向评分匹配分析
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Sense of coherence mediates perceived social support and depressive and anxiety symptoms in cervical cancer patients: a cross-sectional study.心理一致感在宫颈癌患者感知社会支持与抑郁、焦虑症状间的中介作用：一项横断面研究。
BMC Psychiatry. 2023 May 4;23(1):312. doi: 10.1186/s12888-023-04792-y.
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Effect of Comprehensive Care Based on Appropriate Chinese Medicine Techniques on Urinary Retention and Bladder Function Recovery after Total Hysterectomy in Patients with Cervical Cancer.基于适宜中医技术的综合护理对宫颈癌全子宫切除术后尿潴留及膀胱功能恢复的影响。
Comput Math Methods Med. 2022 Jun 30;2022:7495418. doi: 10.1155/2022/7495418. eCollection 2022.
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Proposing a novel care program: reminiscence therapy involved care for anxiety, depression, and quality of life in postoperative cervical cancer patients.提出一种新的护理方案：回忆疗法对术后宫颈癌患者的焦虑、抑郁和生活质量的影响。
Ir J Med Sci. 2022 Oct;191(5):2019-2027. doi: 10.1007/s11845-021-02728-7. Epub 2021 Oct 30.

本文引用的文献

1
The trend and outcome of postsurgical therapy for high-risk early-stage cervical cancer with lymph node metastasis in Japan: a report from the Japan Society of Gynecologic Oncology (JSGO) guidelines evaluation committee.日本淋巴结转移高危早期宫颈癌术后治疗趋势和结局：日本妇科肿瘤学会（JSGO）指南评估委员会报告。
J Gynecol Oncol. 2021 May;32(3):e44. doi: 10.3802/jgo.2021.32.e44.
2
Evidence-Based Treatment Paradigms for Management of Invasive Cervical Carcinoma.浸润性宫颈癌管理的循证治疗模式
J Clin Oncol. 2019 Sep 20;37(27):2472-2489. doi: 10.1200/JCO.18.02303. Epub 2019 Aug 12.
3
Japan Society of Gynecologic Oncology guidelines 2017 for the treatment of uterine cervical cancer.日本妇科肿瘤学会 2017 年子宫颈癌治疗指南。
Int J Clin Oncol. 2019 Jan;24(1):1-19. doi: 10.1007/s10147-018-1351-y. Epub 2018 Oct 5.
4
Annual Report of the Committee on Gynecologic Oncology, Japan Society of Obstetrics and Gynecology: Patient Annual Report for 2014 and Treatment Annual Report for 2009.日本妇产科学会妇科肿瘤委员会年度报告：2014年患者年度报告及2009年治疗年度报告。
J Obstet Gynaecol Res. 2017 Nov;43(11):1667-1677. doi: 10.1111/jog.13450. Epub 2017 Sep 11.
5
Cervical cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.宫颈癌：ESMO 诊断、治疗及随访临床实践指南
Ann Oncol. 2017 Jul 1;28(suppl_4):iv72-iv83. doi: 10.1093/annonc/mdx220.
6
Risk of metachronous ovarian cancer after ovarian conservation in young women with stage I cervical cancer.I期宫颈癌年轻女性保留卵巢后发生异时性卵巢癌的风险。
Am J Obstet Gynecol. 2017 Nov;217(5):580.e1-580.e10. doi: 10.1016/j.ajog.2017.06.019. Epub 2017 Jun 27.
7
Comparison of adjuvant therapy for node-positive clinical stage IB-IIB cervical cancer: Systemic chemotherapy versus pelvic irradiation.淋巴结阳性临床分期IB-IIB期宫颈癌辅助治疗的比较：全身化疗与盆腔放疗。
Int J Cancer. 2017 Sep 1;141(5):1042-1051. doi: 10.1002/ijc.30793. Epub 2017 Jun 8.
8
The issues regarding postoperative adjuvant therapy and prognostic risk factors for patients with stage I-II cervical cancer: A review.I-II期宫颈癌患者术后辅助治疗及预后危险因素相关问题综述
J Obstet Gynaecol Res. 2017 Apr;43(4):617-626. doi: 10.1111/jog.13282. Epub 2017 Feb 11.
9
Treatment of cervical cancer with adjuvant chemotherapy versus adjuvant radiotherapy after radical hysterectomy and systematic lymphadenectomy.根治性子宫切除及系统性淋巴结清扫术后辅助化疗与辅助放疗治疗宫颈癌的比较
J Obstet Gynaecol Res. 2008 Aug;34(4):552-6. doi: 10.1111/j.1447-0756.2008.00739.x.
10
'Is there a role for adjuvant pelvic radiotherapy after radical hysterectomy in early stage cervical cancer?'.早期宫颈癌根治性子宫切除术后辅助盆腔放疗是否有作用？
Int J Gynecol Cancer. 1992 Jan;2(1):56. doi: 10.1046/j.1525-1438.1992.02010056.x.

Should adjuvant chemotherapy be formally studied among patients found to have pelvic lymph node metastases following radical hysterectomy with lymphadenectomy for early-stage cervical cancer?

作者信息

Bujnak Alyssa C, Tewari Krishnansu S

机构信息

Division of Gynecologic Oncology, University of California, Irvine Medical Center, Irvine, CA, USA.

出版信息

J Gynecol Oncol. 2021 Jul;32(4):e62. doi: 10.3802/jgo.2021.32.e62. Epub 2021 Apr 19.

DOI:10.3802/jgo.2021.32.e62
PMID:33908714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8192234/
Abstract
摘要