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[神经心理学的长期新冠症状:神经源性还是精神源性?]

[Neuropsychological long-COVID : neurologic or psychiatric origin?].

作者信息

Benzakour Lamyae, Assal Frédéric, Péron Julie Anne

机构信息

Service de psychiatrie de liaison et d'intervention de crise, Département de psychiatrie, HUG, 1211 Genève 14.

Service de neurologie, Département des neurosciences cliniques, HUG, 1211 Genève 14.

出版信息

Rev Med Suisse. 2021 Apr 28;17(736):822-826.

Abstract

Among the long-COVID symptoms, neuropsychological sequelae are frequent after an infection by SARS-CoV-2, whatever the severity of the respiratory disease in the acute phase. These deficits seem to result from a neurological disorder, but also from psychiatric symptoms. Not only inflammatory components, which can play a major role in the genesis of the neuropsychological sequelae, but also the hypotheses of vascular systemic lesions, the neurotropism of SARS-CoV-2, or the effect of the stress and the hypothalamic-pituitary-adrenal axis (HPA) are suggested. Psychiatric complications due to SSARS-CoV-2 infection would partly explain these neuropsychological sequelae.

摘要

在长期新冠症状中,无论急性期呼吸道疾病的严重程度如何,感染新冠病毒后神经心理后遗症都很常见。这些缺陷似乎是由神经疾病导致的,但也源于精神症状。不仅炎症成分可能在神经心理后遗症的发生中起主要作用,血管系统性病变、新冠病毒的神经嗜性,或应激及下丘脑-垂体-肾上腺轴(HPA)的影响等假说也被提出。新冠病毒感染引起的精神并发症可以部分解释这些神经心理后遗症。

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