Pediatric Cardiology, Stanford University School of Medicine, 750 Welch Road, Suite 325, Palo Alto, CA 94304-5731 USA.
J Invasive Cardiol. 2021 May;33(5):E378-E386. doi: 10.25270/jic/20.00516. Epub 2021 Apr 29.
The objective of this study was to assess procedural outcomes of balloon pulmonary artery (PA) angioplasty procedures after complete repair of tetralogy of Fallot with major aortopulmonary collateral arteries (TOF/MAPCAs).
Our approach to patients with TOF/MAPCAs emphasizes early complete unifocalization and repair. Major PA reinterventions are relatively uncommon. Balloon PA angioplasty is often used, but the effectiveness of balloon PA angioplasty in this population is unknown.
The study cohort comprised patients who underwent complete unifocalization and repair of TOF/ MAPCAs at our center between 2002-2018 and underwent balloon PA angioplasty after repair. To assess immediate procedural outcomes, pre- and postintervention PA measurements were compared.
We reviewed 134 vessels that were dilated a median of 1.1 years after repair in 60 patients (median 2 PA branches per patient). Treated vessels included 15 central, 64 lobar, and 55 segmental branches. The median PA diameter at the level of stenosis increased from 1.9 mm to 3.3 mm (P<.001), and the median diameter increase was 50%. All but 6 treated vessels were enlarged. The stenosis-distal diameter ratio increased from a median of 64% to 89% (P<.001). The median central PA to aortic systolic pressure ratio was 47% before and 39% after intervention (P<.001).
Balloon PA angioplasty was acutely effective at treating most stenoses of reconstructed PA branches after repair of TOF/MAPCAs. Simple angioplasty can be a useful tool in treating isolated or modest stenoses after unifocalization/PA reconstruction surgery using our approach.
本研究旨在评估完全修复法洛四联症伴主肺动脉外侧支(TOF/MAPCAs)后行肺动脉球囊血管成形术的手术结果。
我们治疗 TOF/MAPCAs 患者的方法强调早期完全单灶化和修复。主肺动脉再干预相对少见。球囊肺动脉血管成形术常被使用,但该方法在该人群中的有效性尚不清楚。
研究队列包括 2002 年至 2018 年期间在我们中心行完全单灶化和修复 TOF/MAPCAs 并在修复后行肺动脉球囊血管成形术的患者。为了评估即刻手术结果,比较了介入前后的肺动脉测量值。
我们回顾了 60 例患者的 134 支血管,这些血管在修复后平均 1.1 年进行了扩张(每位患者平均 2 支肺动脉分支)。治疗的血管包括 15 支中央支、64 支肺叶支和 55 支节段支。狭窄部位的肺动脉直径中位数从 1.9mm 增加到 3.3mm(P<.001),直径增加中位数为 50%。除了 6 支治疗的血管外,所有血管均增大。狭窄-远端直径比从中位数 64%增加到 89%(P<.001)。介入前中心肺动脉与主动脉收缩压比值的中位数为 47%,介入后为 39%(P<.001)。
球囊肺动脉血管成形术在治疗 TOF/MAPCAs 修复后重建肺动脉分支的大多数狭窄方面具有即刻疗效。在采用我们的方法进行单灶化/PA 重建手术后,对于孤立或适度狭窄,单纯血管成形术可以作为一种有用的治疗工具。