Implications of Species Differences in Function and Localization of Transporters at the Blood-Testis Barrier.
作者信息
Hau Raymond K, Miller Siennah R, Cherrington Nathan J
机构信息
Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona 85721.
出版信息
Toxicol Sci. 2021 Apr 27;181(1):1-2. doi: 10.1093/toxsci/kfab024.
Abstract
摘要
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本文引用的文献
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J Antimicrob Chemother. 2016 Jul;71(7):1954-65. doi: 10.1093/jac/dkw046. Epub 2016 Apr 13.
2
Localization of multidrug resistance-associated proteins along the blood-testis barrier in rat, macaque, and human testis.多药耐药相关蛋白在大鼠、猕猴和人睾丸血睾屏障中的定位。
Drug Metab Dispos. 2014 Jan;42(1):89-93. doi: 10.1124/dmd.113.054577. Epub 2013 Oct 15.
3
Neonatal exposure to zearalenone induces long term modulation of ABC transporter expression in testis.新生仔猪暴露于玉米赤霉烯酮可诱导睾丸中 ABC 转运蛋白表达的长期调节。
Toxicology. 2013 Aug 9;310:29-38. doi: 10.1016/j.tox.2013.05.002. Epub 2013 May 22.
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Basolateral uptake of nucleosides by Sertoli cells is mediated primarily by equilibrative nucleoside transporter 1.支持细胞基底外侧摄取核苷主要由核苷转运蛋白 1 介导。
J Pharmacol Exp Ther. 2013 Jul;346(1):121-9. doi: 10.1124/jpet.113.203265. Epub 2013 May 2.
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Species differences in drug transporters and implications for translating preclinical findings to humans.药物转运体的种属差异及其对将临床前研究结果转化为人类应用的影响。
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