Degradations of endocrine-disrupting chemicals and pharmaceutical compounds in wastewater with carbon-based nanomaterials: a critical review.

Although water occupies 75% of the earth's surface, only 0.0067% of the total water is available for human activities. These statistics further decline with the population growth and consequent multiplication in the amount of annual waste produced. The demand for clean and safe drinking water has always been a prime concern in the global scenario. Among various types of waste materials, endocrine-disrupting chemicals (EDCs) and pharmaceutical effluents have become a constant threat to the aquatic ecosystem and possess challenges worldwide. Endocrine-disrupting chemicals (EDCs) are a mixed group of emerging concern chemicals with the ability to mimic the mechanisms of biosynthesis, transport, and metabolism of hormones. These chemicals pose various health threats such as early puberty, infertility, obesity, diabetes, reproductive disorders, cancerous tumors, and related disorders (immune cells, hormones' activity, and various organs). On the other hand, pharmaceutical compounds such as antibiotics also harm the natural environment, human health, and soil microbiology. Their low concentration, ranging from a few ng/L to μg/L, gives rise to a micro-pollution phenomenon, which makes it difficult to detect, analyze, and degrade in wastewater treatment plants. Activated carbons (ACs) and other adsorbents, including naturally occurring materials (wood, keratin) are considered as nanomaterials (NMs) reference for the separation of organic pollutants. It is generally acknowledged that mass-transfer phenomena control sorption kinetics at the liquid/solid interface, with retention controlled by the sorbent/sorbate properties. Therefore, the type of interaction (strong or weak van der Waals forces) and the hydrophilic/hydrophobic properties of the adsorbent are two crucial factors. Besides, EDCs and pharmaceutical compound sorption on such kinds of nanoporous solids depend on both the molecule size and charge density. The applications of nanomaterials on non-conservative methods, like advanced oxidation processes or AOPs (e.g., photocatalysis and Fenton reaction), are contemplated as more apt in comparison to conservative technology like reverse osmosis nanofiltration, and adsorption, etc. One of the reasons is that AOPs generate free radicals (hydroxyls), which are strong oxidants for the demineralization of organic compounds and the extreme case that hydroxyl radicals can attack any kinds of pollutants with the generation of only water and carbon dioxide as final products. AOPs may imply the use of NMs as either catalysts or photocatalysts, which improve the selective removal of the target pollutant. Therefore, various literature reviews have revealed that there is a timely need to upgrade the efficiency of the remediation approaches to protect the environment against EDCs and pharmaceuticals adequately. There is currently a lack of definitive risk assessment tools due to their complicated detection and associated insufficiency in the health risk database. Hence, our present review focuses on applying carbon-based nanomaterials to remove EDCs and pharmaceuticals from aqueous systems. The paper covers the effect of these pollutants and photocatalytic methods for treating these compounds in wastewater, along with their limitations and challenges, plausible solutions, and prospects of such techniques.