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单纯括约肌切开术与括约肌切开术联合胆道支架置入治疗胆漏:一家四级医院 10 年经验。

SPHINCTEROTOMY ALONE VERSUS SPHINCTEROTOMY AND BILIARY STENT PLACEMENT IN THE TREATMENT OF BILE LEAKS: 10 YEAR EXPERIENCE AT A QUATERNARY HOSPITAL.

机构信息

Hospital Santa Marcelina, São Paulo, SP, Brasil.

Walter Reed Medical Center, Washington D.C., USA.

出版信息

Arq Gastroenterol. 2021 Jan-Mar;58(1):71-76. doi: 10.1590/S0004-2803.202100000-12.

Abstract

BACKGROUND

Hepatobiliary surgery and hepatic trauma are frequent causes of bile leaks and this feared complication can be safely managed by endoscopic retrograde cholangiopancreatography (ERCP). The approach consists of sphincterotomy alone, biliary stenting or a combination of the two but the optimal form remains unclear.

OBJECTIVE

The aim of this study is to compare sphincterotomy alone versus sphincterotomy plus biliary stent placement in the treatment of post-surgical and traumatic bile leaks.

METHODS

We retrospectively analyzed 31 patients with the final ERCP diagnosis of "bile leak". Data collected included patient demographics, etiology of the leak and the procedure details. The treatment techniques were divided into two groups: sphincterotomy alone vs. sphincterotomy plus biliary stenting. We evaluated the volume of the abdominal surgical drain before and after each procedure and the number of days needed until cessation of drainage post ERCP.

RESULTS

A total of 31 patients (18 men and 3 women; mean age, 51 years) with bile leaks were evaluated. Laparoscopic cholecystectomy was the etiology of the leak in 14 (45%) cases, followed by conventional cholecystectomy in 9 (29%) patients, hepatic trauma in 5 (16%) patients, and hepatectomy secondary to neoplasia in 3 (9.7%) patients. The most frequent location of the leaks was the cystic duct stump with 12 (38.6%) cases, followed by hepatic common duct in 10 (32%) cases, common bile duct in 7 (22%) cases and the liver bed in 2 (6.5%) cases. 71% of the patients were treated with sphincterotomy plus biliary stenting, and 29% with sphincterotomy alone. There was significant difference between the volume drained before and after both procedures (P<0.05). However, when comparing sphincterotomy alone and sphincterotomy plus biliary stenting, regarding the volume drained and the days needed to cessation of drainage, there was no statistical difference in both cases (P>0.005).

CONCLUSION

ERCP remains the first line treatment for bile leaks with no difference between sphincterotomy alone vs sphincterotomy plus stent placement.

摘要

背景

肝胆外科手术和肝外伤是胆汁漏的常见原因,这种令人担忧的并发症可以通过内镜逆行胰胆管造影(ERCP)安全治疗。该方法包括单纯括约肌切开术、胆道支架置入或两者联合应用,但最佳方法仍不清楚。

目的

本研究旨在比较单纯括约肌切开术与括约肌切开术联合胆道支架置入治疗术后和外伤性胆汁漏。

方法

我们回顾性分析了 31 例最终 ERCP 诊断为“胆汁漏”的患者。收集的数据包括患者人口统计学资料、漏出的病因和手术细节。治疗技术分为两组:单纯括约肌切开术与括约肌切开术加胆道支架置入术。我们评估了每个操作前后的腹部外科引流管的体积,以及 ERCP 后停止引流所需的天数。

结果

共评估了 31 例(18 名男性和 3 名女性;平均年龄 51 岁)胆汁漏患者。腹腔镜胆囊切除术是 14 例(45%)漏出的病因,其次是常规胆囊切除术 9 例(29%)、肝外伤 5 例(16%)和肿瘤继发肝切除术 3 例(9.7%)。漏出最常见的部位是胆囊管残端,有 12 例(38.6%),其次是肝总管 10 例(32%)、胆总管 7 例(22%)和肝床 2 例(6.5%)。71%的患者接受了括约肌切开术联合胆道支架置入术,29%的患者接受了单纯括约肌切开术。两种方法治疗前后引流体积均有显著差异(P<0.05)。然而,当比较单纯括约肌切开术和括约肌切开术联合胆道支架置入术时,在引流体积和停止引流所需的天数方面,两种情况均无统计学差异(P>0.005)。

结论

ERCP 仍然是胆汁漏的一线治疗方法,单纯括约肌切开术与括约肌切开术联合支架置入术之间无差异。

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