Holm I A, McLaughlin J F, Feldman K, Stone E F
Division of Congenital Defects, Children's Hospital and Medical Center, Seattle, WA 98105.
Clin Pediatr (Phila). 1988 Jul;27(7):326-9. doi: 10.1177/000992288802700703.
Two children with multiple severe disabilities due to brain destruction by neonatal infection had recurrent hypothermia (less than 34 degrees C) with associated thrombocytopenia (less than 50,000), and clinical hemorrhage. They also had milder, less consistent erythroid and myeloid cell line abnormalities. The hypothermia was presumed to be due to hypothalamic dysfunction. Rewarming was always followed by correction of hematologic problems, but normal temperature was difficult to maintain. Recognition of this entity may improve long-term management of some severely disabled children.
两名因新生儿感染导致脑部受损而患有多种严重残疾的儿童出现反复体温过低（低于34摄氏度），伴有血小板减少（低于50,000）和临床出血。他们还存在较轻且不太一致的红系和髓系细胞系异常。体温过低被推测是由于下丘脑功能障碍所致。复温后血液学问题总是得到纠正，但正常体温难以维持。认识到这一情况可能会改善一些重度残疾儿童的长期管理。
