Liu Y J, Liu H, Wang S B, Xiao Q M, Sun A H, Li Y Q, Wang W Z
Harrison International Peace Hospital of Hebei Medical University, Hengshui 053000, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2021 Apr 20;39(4):258-261. doi: 10.3760/cma.j.cn121094-20200421-00155.
To analyze the correlation and predictive value between early BIS monitoring combined with lactic acid resolution (LCR) and delayed encephalopathy with acute severe carbon monoxide poisoning (ASCMP) . Select 96 cases of our hospital ASCMP patients were analyzed retrospectively in March 2020, and follow-up of 60 days, according to the outcome in patients with acute carbon monoxide poisoning (DEACMP) delayed encephalopathy group with good prognosis, compare two groups of general information, admission BIS average 24 h and 24 h after treatment the LCR, According to the 24h LCR test results, patients were divided into high LCR group (LCR>15%) and low LCR group (LCR≤15%) , analysis the BIS average, the correlation of the LCR with DEACMP and both individual and joint of DEACMP predictive value, Comparing clinical data of patients with high LCR and low LCR. The mean BIS value of the DEACMP group 24 hours after admission was significantly lower than that of the group with good prognosis (< 0.05) . LCR of DEACMP group was significantly lower than that of the group with good prognosis after 24 h treatment (<0.05) . The prevalence of DEACMP in patients with high LCR was significantly lower than that with low LCR (<0.01) ; In the early stage, BIS mean, LCR and DEACMP were negatively correlated (< 0.05) , and the area under the curve predicted by BIS mean, LCR and their combination on DEACMP was 0.799, 0.847 and 0.902, respectively. Early BIS monitoring combined with LCR has a significant correlation with DEACMP, and the combined effect of the two is better. Early BIS combined with LCR detection can provide effective guidance for the prognosis assessment of ASCMP patients.
分析早期脑电双频指数（BIS）监测联合乳酸清除率（LCR）与急性重度一氧化碳中毒（ASCMP）迟发性脑病之间的相关性及预测价值。选取我院2020年3月收治的96例ASCMP患者进行回顾性分析，随访60天，根据急性一氧化碳中毒患者迟发性脑病（DEACMP）预后情况分为预后良好组，比较两组一般资料、入院时BIS均值、治疗24小时后LCR，根据24h LCR检测结果，将患者分为高LCR组（LCR>15%）和低LCR组（LCR≤15%），分析BIS均值、LCR与DEACMP的相关性及两者单独及联合对DEACMP的预测价值，比较高LCR组与低LCR组患者临床资料。DEACMP组入院24小时后BIS均值显著低于预后良好组（<0.05）。治疗24小时后DEACMP组LCR显著低于预后良好组（<0.05）。高LCR组DEACMP患病率显著低于低LCR组（<0.01）；早期BIS均值、LCR与DEACMP呈负相关（<0.05），BIS均值、LCR及其联合预测DEACMP的曲线下面积分别为0.799、0.847和0.902。早期BIS监测联合LCR与DEACMP具有显著相关性，两者联合效果更佳。早期BIS联合LCR检测可为ASCMP患者预后评估提供有效指导。
