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生物聚合物吸附剂在从营养保健品中提取代谢产物方面的发展进展,重点是茄科植物,以及随后的药理学应用。

Advances in the development of biopolymeric adsorbents for the extraction of metabolites from nutraceuticals with emphasis on Solanaceae and subsequent pharmacological applications.

机构信息

Department of Chemistry, School of Mathematical and Natural Sciences, University of Venda, Private Bag X5050, Thohoyandou, 0950, South Africa.

Department of Biochemistry, School of Mathematical and Natural Sciences, University of Venda, Private Bag X5050, Thohoyandou, 0950, South Africa.

出版信息

Carbohydr Polym. 2021 Jul 15;264:118049. doi: 10.1016/j.carbpol.2021.118049. Epub 2021 Apr 7.

Abstract

Biopolymers are renowned for their sustainable, biodegradable, biocompatible and most of them have antitoxic characteristics. These versatile naturally derived compounds include proteins, polynucleotides (RNA and DNA) and polysaccharides. Cellulose and chitosan are the most abundant polysaccharides. Proteins and polysaccharides have been applied as emulsifiers. Additional applications of proteins and polysaccharides include cosmetics, food and wastewater treatment for adsorption of dyes and pesticides. However, more interesting applications of biopolymers are emerging, such as use in transport systems for delivery of plant derived nutraceuticals to sites of inflammation, due to its inherent ability to immobilize different biological and chemical systems. This review aims to give a summary on new trends and complement what is already known in the development of polysaccharides and proteins as adsorbents of nutraceutical compounds. The application of polysaccharides/protein containing the adsorbed Solanum derived nutraceutical compounds for drug deliveryis also reviewed.

摘要

生物聚合物以其可持续性、可生物降解性、生物相容性而闻名,其中大多数还具有抗毒性。这些用途广泛的天然衍生化合物包括蛋白质、多核苷酸(RNA 和 DNA)和多糖。纤维素和壳聚糖是最丰富的多糖。蛋白质和多糖已被用作乳化剂。蛋白质和多糖的其他应用包括化妆品、食品和废水处理,用于吸附染料和农药。然而,生物聚合物的更多有趣应用正在出现,例如在运输系统中用于将植物源性营养保健品递送到炎症部位,因为它具有固载不同生物和化学系统的固有能力。本综述旨在总结多糖和蛋白质作为营养保健品吸附剂的新趋势,并补充其已知的发展情况。还综述了含有吸附的茄属植物来源营养保健品的多糖/蛋白质在药物传递中的应用。

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