Mohta Alpana, Jain Suresh K, Kushwaha Ramesh K, Singh Arti, Gautam Umesh, Nyati Asha
Department of Dermatology, Venereology and Leprosy, GMC, Kota, Rajasthan, India.
Indian J Dermatol. 2021 Jan-Feb;66(1):44-48. doi: 10.4103/ijd.IJD_290_19.
Extra-genital warts (EGWs) affect 7-10% of population. Even though a plethora of studies have been conducted to assess the impact of genital warts (GWs) showing a significant impact on the quality of life but surprisingly, barely any data has been collected on the impact of EGWs on quality of life.
This cross-sectional study aimed at comparing the magnitude of EGWs on health-related quality of life and various variables with that of GWs.
The study consisted of two groups of immunocompetent adults, each with 100 patients aged 18 years or above, attending the skin outpatient department at our tertiary center between April 2018 and March 2019 and consented to participate. Group A consisted of patients with EGWs and group B comprised of patients with GWs. All patients were asked to fulfill the validated Hindi hard copy of the Dermatology Life Quality Index (DLQI) questionnaire.
The mean DLQI score of patients with EGWs was 8.73 ± 0.84 and that of patients with GWs was 5.83 ± 0.83 ( = 0.026). In group A, those affected the most were patients with warts on multiple exposed sites (mean DLQI score of 14), followed by warts on feet (mean DLQI score of 10.69), followed by warts on hands (DLQI score of 9.12), and facial warts (DLQI score of 6.80). Patients with a prior history of failed treatment and/or a longer duration of illness had a higher level of dissatisfaction. To the best of our knowledge, no such study has been conducted in the past in our country.
EGWs inflict a severe negative impact on the quality of life. Owing to its notorious persistence and recurrence, healthcare professionals must educate patients on how to prevent the spread and recurrence, discuss details of available treatment modalities while keeping in view the psychological and sociological impact.
生殖器外疣（EGWs）影响7% - 10%的人群。尽管已经进行了大量研究来评估尖锐湿疣（GWs）对生活质量的影响，显示出其对生活质量有显著影响，但令人惊讶的是，几乎没有收集到关于生殖器外疣对生活质量影响的数据。
本横断面研究旨在比较生殖器外疣与尖锐湿疣对健康相关生活质量及各种变量影响的程度。
该研究由两组免疫功能正常的成年人组成，每组100名年龄在18岁及以上的患者，于2018年4月至2019年3月期间在我们的三级中心皮肤科门诊就诊并同意参与。A组为生殖器外疣患者，B组为尖锐湿疣患者。所有患者均被要求填写经过验证的印地语硬拷贝版皮肤病生活质量指数（DLQI）问卷。
生殖器外疣患者的平均DLQI评分为8.73 ± 0.84，尖锐湿疣患者的平均DLQI评分为5.83 ± 0.83（P = 0.026）。在A组中，受影响最大的是多个暴露部位有疣的患者（平均DLQI评分为14），其次是足部有疣的患者（平均DLQI评分为10.69），然后是手部有疣的患者（DLQI评分为9.12），以及面部有疣的患者（DLQI评分为6.80）。有治疗失败既往史和/或病程较长的患者不满程度较高。据我们所知，我国过去尚未进行过此类研究。
生殖器外疣对生活质量造成严重负面影响。由于其臭名昭著的持续性和复发性，医疗保健专业人员必须教育患者如何预防传播和复发，在考虑心理和社会学影响的同时讨论可用治疗方式的细节。
