Kim Sunmi, Kwak Insuk, Park Gyeong-Hun
Department of Family Medicine, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, Korea.
Department of Anesthesiology, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea.
Ann Dermatol. 2019 Feb;31(1):51-58. doi: 10.5021/ad.2019.31.1.51. Epub 2019 Jan 2.
The effects of diabetes mellitus (DM) on mortality and morbidities in burn patients have not been sufficiently elucidated.
The present study aimed to investigate the effects of DM on the mortality, length of hospital stay, and number of operations in burn patients.
A retrospective cohort study was performed using medical records of 3,220 burn patients. Multiple logistic regression, linear regression, and Poisson regression models were used to determine whether DM increases mortality in patients with burn injury, whether DM prolongs length of hospital stay in burn survivors, and whether DM increases the number of operations in burn survivors, respectively.
After adjusting for potential confounding factors, DM significantly increased odds of death in burn patients (adjusted odds ratio 3.225 [95% confidence interval 1.4057.400], =0.006). DM also increased the mean length of hospital stay in burn survivors (adjusted mean ratio 1.312 [95% confidence interval 1.1981.437], <0.001). Furthermore, DM significantly increased the mean number of operations in burn survivors (adjusted mean ratio 1.576 [95% confidence interval 1.391~1.785], <0.001).
DM increases mortality, elongates hospital stay and makes more operations required in patients with burn injury.
糖尿病（DM）对烧伤患者死亡率和发病率的影响尚未得到充分阐明。
本研究旨在探讨糖尿病对烧伤患者死亡率、住院时间和手术次数的影响。
采用3220例烧伤患者的病历进行回顾性队列研究。分别使用多元逻辑回归、线性回归和泊松回归模型来确定糖尿病是否会增加烧伤患者的死亡率，是否会延长烧伤幸存者的住院时间，以及是否会增加烧伤幸存者的手术次数。
在调整潜在混杂因素后，糖尿病显著增加了烧伤患者的死亡几率（调整后的优势比为3.225[95%置信区间1.4057.400]，P=0.006）。糖尿病还增加了烧伤幸存者的平均住院时间（调整后的平均比率为1.312[95%置信区间1.1981.437]，P<0.001）。此外，糖尿病显著增加了烧伤幸存者的平均手术次数（调整后的平均比率为1.576[95%置信区间1.391~1.785]，P<0.001）。
糖尿病会增加烧伤患者的死亡率，延长住院时间，并使患者需要进行更多手术。
