细胞衔接蛋白-2在恶性黑色素瘤中上调并促进肿瘤生长。 - Suppr

Cytohesin-2 Is Upregulated in Malignant Melanoma and Contributes to Tumor Growth.

作者信息

Lee Yoon Jin, Bae Jin Ho, Kim Woo Il, Kim Jun Hyuk, Cho Sung Woo, Lee Sang Hoon, Jeon Jin Seok, Nam Hae Seon, Lee Seon Hwa, Lee Sang Han, Cho Moon Kyun

机构信息

Molecular Cancer Research, Soonchunhyang University College of Medicine, Cheonan, Korea.

Department of Dermatology, Soonchunhyang University Seoul Hospital, Seoul, Korea.

出版信息

Ann Dermatol. 2019 Feb;31(1):93-96. doi: 10.5021/ad.2019.31.1.93. Epub 2019 Jan 2.

DOI:10.5021/ad.2019.31.1.93

PMID:33911549

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7992705/

Abstract

摘要

相似文献

Cytohesin-2 Is Upregulated in Malignant Melanoma and Contributes to Tumor Growth.细胞衔接蛋白-2在恶性黑色素瘤中上调并促进肿瘤生长。

Ann Dermatol. 2019 Feb;31(1):93-96. doi: 10.5021/ad.2019.31.1.93. Epub 2019 Jan 2.

Cytohesin-2 as a novel prognostic marker for hepatocellular carcinoma.细胞连接蛋白-2 作为肝细胞癌的一种新型预后标志物。

Oncol Rep. 2013 Jun;29(6):2211-8. doi: 10.3892/or.2013.2366. Epub 2013 Mar 26.

Cytohesin-1 regulates fMLF-mediated activation and functions of the β2 integrin Mac-1 in human neutrophils.细胞松弛素-1 调节人中性粒细胞中 fMLF 介导的 β2 整合素 Mac-1 的激活和功能。

J Leukoc Biol. 2011 Jun;89(6):823-36. doi: 10.1189/jlb.0410222. Epub 2011 Jan 13.

The N-terminal coiled coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with the scaffolding protein CASP.鸟嘌呤核苷酸交换因子的细胞粘附素/ARNO家族的N端卷曲螺旋结构域与支架蛋白CASP相互作用。

J Biol Chem. 2002 Aug 30;277(35):32302-9. doi: 10.1074/jbc.M202898200. Epub 2002 Jun 6.

Valproic acid-inducible Arl4D and cytohesin-2/ARNO, acting through the downstream Arf6, regulate neurite outgrowth in N1E-115 cells.丙戊酸诱导的Arl4D和细胞衔接蛋白-2/ARNO通过下游的Arf6发挥作用，调节N1E-115细胞中的神经突生长。

Exp Cell Res. 2009 Jul 15;315(12):2043-52. doi: 10.1016/j.yexcr.2009.03.012. Epub 2009 Mar 25.

Arf6 guanine-nucleotide exchange factor cytohesin-2 regulates myelination in nerves.Arf6鸟嘌呤核苷酸交换因子细胞黏附分子2调节神经髓鞘形成。

Biochem Biophys Res Commun. 2015 May 8;460(3):819-25. doi: 10.1016/j.bbrc.2015.03.113. Epub 2015 Mar 28.

Interaction protein for cytohesin exchange factors 1 (IPCEF1) binds cytohesin 2 and modifies its activity.细胞衔接蛋白交换因子1相互作用蛋白（IPCEF1）与细胞衔接蛋白2结合并改变其活性。

J Biol Chem. 2003 Oct 31;278(44):43460-9. doi: 10.1074/jbc.M304078200. Epub 2003 Aug 14.

Signaling through Arf6 guanine-nucleotide exchange factor cytohesin-1 regulates migration in Schwann cells.Arf6 鸟嘌呤核苷酸交换因子细胞松弛素-1 通过信号转导调节施万细胞的迁移。

Cell Signal. 2013 Jun;25(6):1379-87. doi: 10.1016/j.cellsig.2013.03.008. Epub 2013 Mar 19.

Structural elements of ADP-ribosylation factor 1 required for functional interaction with cytohesin-1.与细胞黏附素-1功能相互作用所需的ADP核糖基化因子1的结构元件。

J Biol Chem. 1999 Apr 30;274(18):12438-44. doi: 10.1074/jbc.274.18.12438.

Inhibition of smooth muscle contraction and ARF6 activity by the inhibitor for cytohesin GEFs, secinH3, in the human prostate.细胞松弛素 GEFs 抑制剂 secinH3 抑制人前列腺平滑肌收缩和 ARF6 活性。

Am J Physiol Renal Physiol. 2018 Jan 1;314(1):F47-F57. doi: 10.1152/ajprenal.00125.2017. Epub 2017 Aug 30.

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Cytohesin-4/ARF6 facilitates the progression of acute myeloid leukemia through activating PIK3R5/PI3K/AKT pathway.细胞衔接蛋白4/ADP核糖基化因子6通过激活PIK3R5/磷脂酰肌醇-3激酶/蛋白激酶B信号通路促进急性髓系白血病的进展。

iScience. 2025 May 12;28(6):112634. doi: 10.1016/j.isci.2025.112634. eCollection 2025 Jun 20.

Integrated analysis and validation reveal CYTH4 as a potential prognostic biomarker in acute myeloid leukemia.综合分析与验证揭示CYTH4作为急性髓系白血病潜在的预后生物标志物。

Oncol Lett. 2024 Jan 16;27(3):103. doi: 10.3892/ol.2024.14236. eCollection 2024 Mar.

Cytohesin-4 Upregulation in Glioma-Associated M2 Macrophages Is Correlated with Pyroptosis and Poor Prognosis.胶质瘤相关M2巨噬细胞中细胞衔接蛋白4的上调与细胞焦亡及不良预后相关。

J Mol Neurosci. 2023 Mar;73(2-3):143-158. doi: 10.1007/s12031-023-02104-3. Epub 2023 Feb 7.

本文引用的文献

Cytohesin 2/ARF6 regulates preadipocyte migration through the activation of ERK1/2.细胞松弛素 2/ARF6 通过激活 ERK1/2 调节前脂肪细胞迁移。

Biochem Pharmacol. 2014 Dec 15;92(4):651-60. doi: 10.1016/j.bcp.2014.09.023. Epub 2014 Oct 20.

Cytohesins/ARNO: the function in colorectal cancer cells.细胞衔接蛋白/ARNO：在结肠癌细胞中的功能

PLoS One. 2014 Mar 11;9(3):e90997. doi: 10.1371/journal.pone.0090997. eCollection 2014.

Cytohesin-2 as a novel prognostic marker for hepatocellular carcinoma.细胞连接蛋白-2 作为肝细胞癌的一种新型预后标志物。

Oncol Rep. 2013 Jun;29(6):2211-8. doi: 10.3892/or.2013.2366. Epub 2013 Mar 26.

ARNO regulates VEGF-dependent tissue responses by stabilizing endothelial VEGFR-2 surface expression.ARNO 通过稳定内皮 VEGFR-2 表面表达来调节 VEGF 依赖性组织反应。

Cardiovasc Res. 2012 Jan 1;93(1):111-9. doi: 10.1093/cvr/cvr265. Epub 2011 Oct 13.

The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling.CNK1 支架结合细胞黏附蛋白并促进胰岛素信号通路。

Genes Dev. 2010 Jul 15;24(14):1496-506. doi: 10.1101/gad.1904610.

ADP-ribosylation factor 6 regulates tumorigenic and invasive properties in vivo.ADP核糖基化因子6在体内调节肿瘤发生和侵袭特性。

Cancer Res. 2009 Mar 15;69(6):2201-9. doi: 10.1158/0008-5472.CAN-08-1301. Epub 2009 Mar 10.

Regulation of Arf activation: the Sec7 family of guanine nucleotide exchange factors.Arf激活的调控：鸟嘌呤核苷酸交换因子的Sec7家族。

Traffic. 2007 Nov;8(11):1476-85. doi: 10.1111/j.1600-0854.2007.00634.x. Epub 2007 Sep 10.

Guanine nucleotide exchange factors of the cytohesin family and their roles in signal transduction.细胞衔接蛋白家族的鸟嘌呤核苷酸交换因子及其在信号转导中的作用。

Immunol Rev. 2007 Aug;218:102-13. doi: 10.1111/j.1600-065X.2007.00542.x.

Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D.ARNO对ARF6的激活通过Rac1和磷脂酶D的下游激活来刺激上皮细胞迁移。

J Cell Biol. 2001 Aug 6;154(3):599-610. doi: 10.1083/jcb.200104019. Epub 2001 Jul 30.

Molecules in the ARF orbit.处于ARF轨道中的分子。

J Biol Chem. 1998 Aug 21;273(34):21431-4. doi: 10.1074/jbc.273.34.21431.

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Cytohesin-2 Is Upregulated in Malignant Melanoma and Contributes to Tumor Growth.

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