默克尔细胞癌13例报告：单中心经验及文献综述
A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature.
作者信息
Yazici Serkan, Irmak Yazici Elif, Balaban Adim Saduman, Bulbul Baskan Emel, Aydoğan Kenan, Saricaoğlu Hayriye
机构信息
Department of Dermatology and Venereology, Uludag University School of Medicine, Bursa, Turkey.
Department of Pathology, Uludag University School of Medicine, Bursa, Turkey.
出版信息
Ann Dermatol. 2019 Jun;31(3):272-278. doi: 10.5021/ad.2019.31.3.272. Epub 2019 May 1.
BACKGROUND
There is limited data knowledge of Merkel cell carcinoma (MCC) in Turkey aside from a few case reports.
OBJECTIVE
The aim of this study was to describe the clinical characteristics, demographic features, therapeutic parameters, and outcome of primary cutaneous MCC cases from Turkey.
METHODS
Digital medical records of the 13 MCC patients who were followed-up at a tertiary referral center were retrospectively analyzed. Clinic, demographic, tumor characteristics, and survival of the patients were retrieved.
RESULTS
Most of our patients were elderly. Female predominance was noticed. The most common primary site of the tumors was the lower extremities. The overall survival was 42 months, 68% at first year, 68% at third years, and 29% at fifth years.
CONCLUSION
This is the first largest report from Turkish population with female predominance, and lower extremity tendency.
背景
除了少数病例报告外，土耳其关于默克尔细胞癌（MCC）的数据知识有限。
目的
本研究的目的是描述来自土耳其的原发性皮肤MCC病例的临床特征、人口统计学特征、治疗参数和结局。
方法
回顾性分析了在一家三级转诊中心接受随访的13例MCC患者的数字医疗记录。检索了患者的临床、人口统计学、肿瘤特征和生存率。
结果
我们的大多数患者为老年人。注意到女性占优势。肿瘤最常见的原发部位是下肢。总生存期为42个月，第一年为68%，第三年为68%，第五年为29%。
结论
这是来自土耳其人群的第一份最大规模报告，具有女性占优势和下肢倾向的特点。
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