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视交叉和胼胝体的矢状面横断会导致猫出现视觉分裂脑:对视优势以及视觉皮层中细胞反应性的影响。

Midsagittal transection of the optic chiasm and the corpus callosum induces visual split brain in cats: the effect on ocular dominance and responsiveness to cells in the visual cortex.

作者信息

Yinon U, Chen M, Hammer A

机构信息

Physiological Laboratory, Maurice and Gabriela Goldschleger Eye Research Institute, Tel-Aviv University Sackler Faculty of Medicine, Chaim Sheba Medical Center, Tel-Hashomer, Israel.

出版信息

Exp Neurol. 1988 Jul;101(1):107-13. doi: 10.1016/0014-4886(88)90068-4.

DOI:10.1016/0014-4886(88)90068-4
PMID:3391253
Abstract

The geniculocortical pathways from the contralateral eye and the callosal pathway were interrupted in cats in order to study how cortical cells are influenced by changes induced in the interhemispheric transfer of visual information. Unit recording was carried out from areas 17 and 18 boundary, the callosal projection zone. The ocular dominance distribution of cortical cells showed absence of interhemispheric interaction. The visual areas in the two sides of the brain thus functioned independently, presenting a condition of visual split brain. This also has been reflected by the absence of compensatory visual inputs via an alternative commissural pathway. Furthermore, remarkable diminution in the excitability level was found as indicated by the reduction in the proportion of visually responsive cells. Finally, the results of the split brain cat reflect the condition of the individual operations from which it is composed.

摘要

为了研究皮层细胞如何受到视觉信息半球间传递变化的影响,在猫身上中断了来自对侧眼的膝状皮层通路和胼胝体通路。在17区和18区边界(胼胝体投射区)进行了单位记录。皮层细胞的眼优势分布显示半球间相互作用缺失。大脑两侧的视觉区域因此独立运作,呈现出视觉裂脑的状态。这也通过缺乏经由另一条连合通路的代偿性视觉输入得以体现。此外,如视觉反应性细胞比例的降低所示,发现兴奋性水平显著降低。最后,裂脑猫的结果反映了构成其个体运作的状况。

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