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[缝合材料在结肠吻合口愈合中作用的实验研究。力学与组织学研究]

[Experimental studies on the role of suture materials in the healing of anastomoses of the colon. Mechanical and histological study].

作者信息

Gioffrè L, Spinelli F, Franchi A, Di Giustino A

出版信息

Minerva Chir. 1977 Oct 31;32(20):1275-86.

PMID:339128
Abstract

The relation between suture material and consolidation and healing in operations on the colon was investigated by using silk and catgut in one group of disinfected stray dogs subjected to right or left hemicolectomy and resection of the transverse portion, and a synthetic reabsorbable material (polyglycolic acid) in another. The following parameters were assessed following removal of the segment containing the anastomosis after various periods of time: resistance to biomechanical tests, stenosis of the lumen, extent and duration of inflammation and regeneration at the edge. Reabsorbable material was associated with less overall inflammation and healing was more rapid. Consolidation of the suture was not significantly different in the two groups.

摘要

通过在一组接受右半结肠切除术、左半结肠切除术和横结肠部分切除术的消毒流浪狗中,一组使用丝线和肠线,另一组使用合成可吸收材料(聚乙醇酸),研究了结肠手术中缝合材料与愈合及巩固之间的关系。在不同时间段后取出包含吻合口的肠段后,评估以下参数:生物力学测试的抗性、管腔狭窄、边缘炎症和再生的程度及持续时间。可吸收材料引起的总体炎症较少,愈合更快。两组的缝合巩固情况无显著差异。

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