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评论“组蛋白去乙酰化酶抑制剂 quisinostat 作为治疗食管鳞癌的治疗剂的临床前评估”。

Comment on "Preclinical assessment of histone deacetylase inhibitor quisinostat as a therapeutic agent against esophageal squamous cell carcinoma".

机构信息

Department of Oncology, Affiliated Hospital of Guangdong Medical University, No. 27 South of Ren Min Road, Zhanjiang, 524200, Guangdong, China.

出版信息

Invest New Drugs. 2021 Oct;39(5):1454-1455. doi: 10.1007/s10637-021-01124-3. Epub 2021 Apr 28.

Abstract

Recently, we read a paper "Preclinical assessment of histone deacetylase inhibitor quisinostat as a therapeutic agent against esophageal squamous cell carcinoma" published in Investigational New Drugs. Quisinostat may be a promising drug candidate for the treatment of esophageal squamous cell carcinoma. However, some problems existing in the methods part of this paper are worthy of comment.

摘要

最近,我们阅读了一篇发表在《新药研究》上的题为“组蛋白去乙酰化酶抑制剂 quisinostat 治疗食管鳞癌的临床前评估”的论文。Quisinostat 可能是治疗食管鳞癌的一种很有前途的候选药物。然而,该论文方法部分存在的一些问题值得讨论。

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