Sen D K, Sivanesaratnam V, Sivanathan R, Pathmanathan R
Department of Obstetrics and Gynecology, University of Singapore.
Gynecol Oncol. 1988 Jul;30(3):321-8. doi: 10.1016/0090-8258(88)90246-6.
Results of treatment of 9 cases of pure immature teratoma of the ovary seen at the University Hospital, Kuala Lumpur, are presented. Six patients were in Stage 1 and three in Stage 3. A majority of them had grade 2 or 3 tumors. Four patients in Stage 1 had the conservative surgery of salpingo-oophorectomy performed, the more radical procedure of total hysterectomy, bilateral salpingo-oophorectomy omentectomy, and tumor debulking where feasible being carried out in the others. Adjuvant chemotherapy consisted of either pulsed cyclophosphamide, VAC (vincristine, actinomycin D, and cyclophosphamide) or PVB (cis-platinum, vinblastine, bleomycin) regimes. Seven patients have survived for periods up to 9 years with no clinical evidence of disease.
本文介绍了吉隆坡大学医院收治的9例卵巢纯未成熟畸胎瘤的治疗结果。6例患者为Ⅰ期，3例为Ⅲ期。大多数患者的肿瘤为2级或3级。Ⅰ期的4例患者接受了保留输卵管卵巢切除术的保守手术，其他患者则进行了更激进的全子宫切除术、双侧输卵管卵巢切除术、大网膜切除术，并在可行的情况下进行肿瘤减灭术。辅助化疗采用脉冲环磷酰胺、VAC（长春新碱、放线菌素D和环磷酰胺）或PVB（顺铂、长春花碱、博来霉素）方案。7例患者已存活长达9年，无疾病临床证据。
