比较全氟癸烷和硅油作为巨大裂孔性视网膜脱离相关视网膜脱离的初始眼内填充物。

Comparison of Perfluorodecalin and Silicone Oil as Initial Tamponade for Giant Retinal Tear-Associated Retinal Detachment.

机构信息

Bristol Eye Hospital, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom.

出版信息

Ophthalmologica. 2021;244(3):218-222. doi: 10.1159/000516520. Epub 2021 May 3.

DOI:10.1159/000516520

PMID:33915541

Abstract

INTRODUCTION

To compare visual outcomes and complication rates of giant retinal tear-associated retinal detachment (GRT-RD) cases treated with short-term perfluorodecalin (PFD) tamponade versus silicone oil (SiO).

METHODS

Database analysis of patients with GRT-RD operated on in the period from 1 January 2014 to 31 December 2019.

RESULTS

Forty-five patients were operated for GRT-RD using PFD or SiO during this period. Two children, 7 patients receiving gas tamponade, and 2 lost to follow-up were excluded. Eighteen eyes (40%) received PFD and 27 (60%) received SiO. There were 15/18 (83%) macula-sparing cases in the PFD group and 18/27 (67%) in the SiO group (p = 0.13). The mean duration of oil tamponade was 91 days for SiO and 7.6 days for PFD (p < 0.0001). The mean length of follow-up was 274.5 days for PFD and 668.9 days for SiO. The mean BCVA was 6/18 (63.4 ± 26.0 ETDRS letters) for SiO and 6/12 (72.9 ± 12.7 ETDRS letters) for PFD (p = 0.42). Analysing macula-sparing pseudophakic eyes, the BCVA was 6/12 (67.4 ± 25.9 letters, n = 18) for SiO eyes and 6/9 (76.8 ± 9.9 letters, n = 11) for PFD eyes (p = 0.54). The recurrence rate was 22% (6/27) for SiO and 6% (1/18) for PFD (p = 0.12). The rate of cystoid macular oedema (CMO) was 22% for SiO and 22% for PFD. Epiretinal membrane (ERM) was found in 26% of SiO cases and 22% of PFD cases. Loss of vision after oil removal was not observed. Seven eyes (26%) receiving SiO and none receiving PFD developed chronic ocular hypertension (OHT) (p = 0.02).

CONCLUSIONS

Short-term tamponade with PFD for GRT-RD appears similar to tamponade with SiO in terms of the visual outcomes and complication rates.

摘要

简介

比较短期全氟萘烷（PFD）与硅油（SiO）填充治疗巨大裂孔性视网膜脱离伴视网膜脱离（GRT-RD）的视力结果和并发症发生率。

方法

对 2014 年 1 月 1 日至 2019 年 12 月 31 日期间接受 GRT-RD 手术的患者进行数据库分析。

结果

在此期间，有 45 名患者因 GRT-RD 接受 PFD 或 SiO 治疗。2 名儿童、7 名接受气体填充的患者和 2 名失访患者被排除在外。18 只眼（40%）接受 PFD 治疗，27 只眼（60%）接受 SiO 治疗。PFD 组有 15/18（83%）黄斑保存病例，SiO 组有 18/27（67%）（p = 0.13）。SiO 组硅油填充的平均持续时间为 91 天，PFD 组为 7.6 天（p < 0.0001）。PFD 组的平均随访时间为 274.5 天，SiO 组为 668.9 天。SiO 组的平均 BCVA 为 6/18（63.4 ± 26.0 ETDRS 字母），PFD 组为 6/12（72.9 ± 12.7 ETDRS 字母）（p = 0.42）。分析黄斑保存的假晶状体眼，SiO 眼的 BCVA 为 6/12（67.4 ± 25.9 字母，n = 18），PFD 眼为 6/9（76.8 ± 9.9 字母，n = 11）（p = 0.54）。SiO 组的复发率为 22%（6/27），PFD 组为 6%（1/18）（p = 0.12）。SiO 组的囊样黄斑水肿（CME）发生率为 22%，PFD 组为 22%。SiO 组发现 26%的眼后膜（ERM），PFD 组发现 22%的眼后膜。未观察到油取出后视力丧失。7 只接受 SiO 治疗的眼（26%）和未接受 PFD 治疗的眼均发生慢性眼压升高（OHT）（p = 0.02）。