缺血性二尖瓣反流：一种治疗方法不断发展的多方面综合征。
Ischemic Mitral Regurgitation: A Multifaceted Syndrome with Evolving Therapies.
作者信息
Vinciguerra Mattia, Grigioni Francesco, Romiti Silvia, Benfari Giovanni, Rose David, Spadaccio Cristiano, Cimino Sara, De Bellis Antonio, Greco Ernesto
机构信息
Department of Clinical, Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Unit of Cardiovascular Sciences, Department of Medicine Campus Bio-Medico, University of Rome, 00128 Rome, Italy.
出版信息
Biomedicines. 2021 Apr 21;9(5):447. doi: 10.3390/biomedicines9050447.
Dysfunction of the left ventricle (LV) with impaired contractility following chronic ischemia or acute myocardial infarction (AMI) is the main cause of ischemic mitral regurgitation (IMR), leading to moderate and moderate-to-severe mitral regurgitation (MR). The site of AMI exerts a specific influence determining different patterns of adverse LV remodeling. In general, inferior-posterior AMI is more frequently associated with regional structural changes than the anterolateral one, which is associated with global adverse LV remodeling, ultimately leading to different phenotypes of IMR. In this narrative review, starting from the aforementioned categorization, we proceed to describe current knowledge regarding surgical approaches in the management of IMR.
慢性缺血或急性心肌梗死（AMI）后左心室（LV）功能障碍伴收缩力受损是缺血性二尖瓣反流（IMR）的主要原因，导致中度和中重度二尖瓣反流（MR）。AMI的部位对左心室不良重构的不同模式有特定影响。一般来说，下后壁AMI比前侧壁AMI更常与局部结构变化相关，前侧壁AMI与左心室整体不良重构相关，最终导致不同表型的IMR。在这篇叙述性综述中，我们从上述分类出发，继续描述目前关于IMR治疗中手术方法的知识。
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