Department of Otorhinolaryngology and Maxillofacial Surgery, Military University Hospital, 16902 Prague, Czech Republic.
Third Faculty of Medicine, Charles University, 10000 Prague, Czech Republic.
Int J Environ Res Public Health. 2021 Apr 18;18(8):4300. doi: 10.3390/ijerph18084300.
Total thyroidectomy (TT) is one of the most common surgical endocrine surgeries. Voice impairment after TT can occur not only in patients with recurrent laryngeal nerve (RLN) transient paralysis, but also in cases of normal vocal cord mobility. To compare voice limits using a speech range profile (SRP) in patients before and 14 days after TT and to investigate the influence of the early results of voice quality after TT on the personal lives of patients. We focused on the perception of voice change before and shortly after TT. A retrospective study, in the period 2018-2020, included 65 patients aged 22-75 years. We compared two groups of patients: group I ( = 45) (without RLN paresis) and group II ( = 20) (with early transient postoperative RLN paresis). Patients underwent video flexible laryngocopy, SRP, and Voice Handicap Index-30 (VHI-30). In group I, the mean values of F (maximum frequency) and I (maximum intensity) decreased in women (both = 0.001), and VHI-30 increased ( = 0.001). In group II after TT in women, the mean F and I values decreased ( = 0.005 and = 0.034), and the frequency range of the voice was reduced from 5 to 2 semitones. The dynamic range of the voice was reduced by 3.4 dB in women and 5.1 dB in men.VHI-30 increased ( = 0.001). The study documented a worsening of the mean values of SRP, VHI-30, and voice parameters of patients in group II. Voice disorders also occurred in group I without RLN paresis. Non-paretic causes can also contribute to voice damage after TT. SRP and VHI-30 are suitable tools for comparing voice status in two groups of patients, including those with dysphonia. Our data support the claim that the diagnosis of a thyroid cancer does not necessarily imply a higher postoperative risk of impaired voice quality for the patient.
甲状腺全切除术(TT)是最常见的内分泌外科手术之一。甲状腺全切除术后不仅可发生于喉返神经(RLN)暂时性麻痹的患者,也可发生于声带运动正常的患者。本研究旨在通过嗓音障碍指数量表(VHI-30)比较 TT 前后的嗓音范围,探讨 TT 后早期嗓音质量对患者生活的影响。我们主要关注 TT 前后患者对嗓音变化的感知。
本研究回顾性分析了 2018 年至 2020 年期间的 65 例年龄在 22-75 岁的患者。我们比较了两组患者:I 组(45 例)(无 RLN 麻痹)和 II 组(20 例)(早期暂时性术后 RLN 麻痹)。所有患者均接受了视频软式喉镜检查、嗓音障碍指数量表(VHI-30)和嗓音频谱分析。I 组中,女性患者的 F(最大频率)和 I(最大强度)平均值下降(均为 P<0.001),VHI-30 增加(P<0.001)。TT 后,II 组中女性患者的 F 和 I 平均值下降(分别为 P=0.005 和 P=0.034),嗓音频率范围降低 5 个半音。女性患者的嗓音动态范围降低 3.4dB,男性患者降低 5.1dB,VHI-30 增加(P<0.001)。
本研究记录了 II 组患者的嗓音频谱分析、VHI-30 以及嗓音参数的平均值恶化。即使无 RLN 麻痹的 I 组患者也发生了嗓音障碍。非麻痹性原因也可能导致 TT 后嗓音受损。嗓音频谱分析和 VHI-30 是比较两组患者嗓音状况的合适工具,包括有嗓音障碍的患者。我们的数据支持以下观点,即诊断为甲状腺癌并不一定意味着患者术后嗓音质量受损的风险更高。