Laboratoire de Chimie des Matériaux Moléculaires, Université de Strasbourg et CNRS (UMR 7402 LIMA), Ecole Européenne de Chimie, Polymères et Matériaux, 25 rue Becquerel, CEDEX 2, 67087 Strasbourg, France.
Institut de Chimie, Université de Neuchâtel, Avenue de Bellevaux 51, 2000 Neuchâtel, Switzerland.
Molecules. 2021 Apr 18;26(8):2358. doi: 10.3390/molecules26082358.
With their ten peripheral substituents, pillar[5]arenes are attractive compact scaffolds for the construction of nanomaterials with a controlled number of functional groups distributed around the macrocyclic core. This review paper is focused on the functionalization of pillar[5]arene derivatives with small dendrons to generate dendrimer-like nanomaterials and bioactive compounds. Examples include non-viral gene vectors, bioactive glycoclusters, and liquid-crystalline materials.
具有十个外围取代基的柱[5]芳烃是构建具有受控数量的功能基团分布在大环核心周围的纳米材料的有吸引力的紧凑支架。本文综述了用小分子树状大分子对柱[5]芳烃衍生物进行功能化,以生成类似树状大分子的纳米材料和生物活性化合物。例子包括非病毒基因载体、生物活性糖簇和液晶材料。