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子宫切除术患者性功能评估的临床试验系统评价

A Systematic Review of Clinical Trials Assessing Sexuality in Hysterectomized Patients.

机构信息

Urology Services, University Hospital of Vinalopó, 03293 Elche, Alicante, Spain.

Urology Services, University Hospital of San Juan de Alicante, 03550 San Juan de Alicante, Alicante, Spain.

出版信息

Int J Environ Res Public Health. 2021 Apr 10;18(8):3994. doi: 10.3390/ijerph18083994.

Abstract

In hysterectomized patients, even though there is still controversy, evidence indicates that in the short term, the vaginal approach shows benefits over the laparoscopic approach, as it is less invasive, faster and less costly. However, the quality of sexual life has not been systematically reviewed in terms of the approach adopted. Through a systematic review, we analyzed (CRD42020158465 in PROSPERO) the impact of hysterectomy on sexual quality and whether there are differences according to the surgical procedure (abdominal or vaginal) for noncancer patients. MEDLINE (through PubMed), Embase, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov and Scopus were reviewed to find randomized clinical trials assessing sexuality in noncancer patients undergoing total hysterectomy, comparing vaginal and abdominal (laparoscopic and/or open) surgery. Three studies that assessed the issue under study were finally included. Two of these had a low risk of bias (Cochrane risk of bias tool); one was unclear. There was significant variability in how sexuality was measured, with no differences between the two approaches considered in the review. In conclusion, no evidence was found to support one procedure (abdominal or vaginal) over another for non-oncological hysterectomized patients regarding benefits in terms of sexuality.

摘要

在接受子宫切除术的患者中,尽管仍存在争议,但有证据表明,在短期内,阴道入路比腹腔镜入路具有更少的创伤、更快的速度和更低的成本优势。然而,对于所采用的手术方法,其对性生活质量的影响尚未进行系统评价。通过系统评价,我们分析了(PROSPERO 中的 CRD42020158465)非癌症患者子宫切除术对性生活质量的影响,以及手术方法(腹部或阴道)是否存在差异。我们对 MEDLINE(通过 PubMed)、Embase、Cochrane 对照试验中心注册库、ClinicalTrials.gov 和 Scopus 进行了回顾,以寻找评估非癌症患者全子宫切除术后性生活的随机临床试验,比较阴道和腹部(腹腔镜和/或开放)手术。最终纳入了三项评估研究问题的研究。其中两项研究的偏倚风险较低(Cochrane 偏倚风险工具);一项研究的偏倚风险不明确。对于如何衡量性生活的方法存在很大的差异,在本综述中考虑的两种方法之间没有差异。总之,对于非肿瘤性子宫切除患者,没有证据支持一种手术方法(腹部或阴道)优于另一种手术方法,因为它们在性生活方面都没有获益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7046/8069441/84e1c0c61a5f/ijerph-18-03994-g001.jpg

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