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一种基于采样方式(拭子采样和血液采样)对造血干细胞捐献志愿者保留率的研究:来自中国上海的证据。

A Study on Hematopoietic Stem Cell Donation Volunteer Retention between Swab Sampling Approach and Blood Sampling Approach: Evidence from Shanghai, China.

机构信息

Department of Health Policy and Management, School of Public Health, Fudan University, Shanghai 200032, China.

China Research Center on Disability Issues, Fudan University, Shanghai 200032, China.

出版信息

Int J Environ Res Public Health. 2021 Apr 12;18(8):4027. doi: 10.3390/ijerph18084027.

DOI:10.3390/ijerph18084027
PMID:33921256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8069943/
Abstract

The loss of hematopoietic stem cell donation (HSCD) volunteers is widespread worldwide. This study analyzed the distribution characteristics of volunteer retention between the swab sampling approach and blood sampling approach. The Shanghai branch of the China Bone Marrow Donation Program conducted a telephone follow-up with 18,963 volunteers to understand volunteer retention. Multiple logistic regression was used to analyze the distribution characteristics of volunteer retention between two different sampling approaches, and a forest plot was used to observe the distribution trend. Only 32.37% of the volunteers could be contacted, and the loss of volunteers was severe. The volunteer retention is influenced by sampling approaches and demographic characteristics, and Shanghai natives, the highly educated, and students had better retention. The volunteer retention of the swab group was better among young people and technicians, while the volunteer retention of the blood sample group was lower among public officials and workers, and the volunteer retention in the blood sample group was more significantly affected by changes in population characteristics. To enhance the stability of volunteers, managers should improve the contact channels and frequency, expand the ratio of stable volunteers, strengthen volunteer education in the process of collecting blood samples, and respect individuals' willingness.

摘要

造血干细胞捐献者流失在世界范围内广泛存在。本研究分析了棉拭子采样法和血液采样法两种采样方式下志愿者保留率的分布特征。中国骨髓库上海分库对 18963 名志愿者进行电话随访,了解志愿者保留情况。采用多因素logistic 回归分析两种不同采样方式下志愿者保留率的分布特征,并通过森林图观察分布趋势。仅 32.37%的志愿者可以联系到,志愿者流失严重。志愿者保留率受采样方式和人口统计学特征影响,上海本地人、高学历和学生保留率较好。年轻人和技术人员中棉拭子组的志愿者保留率较好,而公务员和工人中血液样本组的志愿者保留率较低,血液样本组的志愿者保留率受人口特征变化的影响更为显著。为了提高志愿者的稳定性,管理人员应改善联系方式和频率,扩大稳定志愿者的比例,在采血过程中加强志愿者教育,并尊重个人意愿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9329/8069943/cc2efa6455db/ijerph-18-04027-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9329/8069943/9e9571dfdfe7/ijerph-18-04027-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9329/8069943/8c48041784ed/ijerph-18-04027-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9329/8069943/fcb97deb9b52/ijerph-18-04027-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9329/8069943/cc2efa6455db/ijerph-18-04027-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9329/8069943/9e9571dfdfe7/ijerph-18-04027-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9329/8069943/8c48041784ed/ijerph-18-04027-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9329/8069943/fcb97deb9b52/ijerph-18-04027-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9329/8069943/cc2efa6455db/ijerph-18-04027-g004.jpg

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本文引用的文献

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Physical and Psychological Discomfort Experienced by Hematopoietic Stem-Cell Donors.造血干细胞捐献者的身心不适。
Int J Environ Res Public Health. 2020 Mar 30;17(7):2316. doi: 10.3390/ijerph17072316.
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Effect of Educational Program on Knowledge, Attitude, and Willingness of Nursing Students for Hematopoietic Stem-Cell Donation.教育计划对护理学生造血干细胞捐献知识、态度和意愿的影响。
Int J Environ Res Public Health. 2019 Oct 1;16(19):3696. doi: 10.3390/ijerph16193696.
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