Haffaf Y, Letoquart J P, Grosbois B, Lavenac G, Leblay R, Mambrini A
Service de Chirurgie Générale A, CHR de Rennes, Hôpital Sud.
J Chir (Paris). 1988 Apr;125(4):260-3.
Case reports of 43 patients with idiopathic thrombocytopenic purpura (ITP) operated upon from 1975 up to the present were analyzed. After revision of therapeutic indications the predictive prognostic factors for splenectomy, essentially the initial response to corticotherapy, were studied. Findings indicated that splenectomy is effective treatment for ITP since permanent total remissions were obtained in 76% with a morbidity of 16% and a mortality of 2%. Emphasis is placed on the need for minute pre-, intra- and post-operative precautions.
分析了1975年至今接受手术治疗的43例特发性血小板减少性紫癜（ITP）患者的病例报告。在修订治疗指征后，研究了脾切除术的预测性预后因素，主要是对皮质激素治疗的初始反应。结果表明，脾切除术是治疗ITP的有效方法，因为76%的患者获得了永久性完全缓解，发病率为16%，死亡率为2%。强调了术前、术中和术后采取细微预防措施的必要性。
