Hoffer F A, Strand R D, Gebhardt M C
Department of Radiology, Children's Hospital, Boston, MA 02115.
J Pediatr Orthop. 1988 Jul-Aug;8(4):442-4. doi: 10.1097/01241398-198807000-00011.
Three boys had percutaneous biopsies of pyogenic infections of the spine guided by computed tomography (CT). All had typical features of chronic vertebral osteomyelitis, i.e., narrowing of disc space, destruction of the contiguous vertebral endplates, sclerosis of vertebral bodies, and soft tissue swelling as noted on radiographs, CT, and magnetic resonance imaging (MRI). All three had back pain; one was asymptomatic at the time of the biopsy. Culture of the biopsy material grew Staphylococcus aureus in two cases and Salmonella group B in one. If blood cultures are negative, a biopsy of the vertebral body is recommended in order to determine the activity of the process and the type of organism, and its susceptibility to antibiotics. CT-guided percutaneous biopsy is an alternative to open surgical biopsy.
三名男孩在计算机断层扫描（CT）引导下对脊柱的化脓性感染进行了经皮活检。所有患者均具有慢性椎体骨髓炎的典型特征，即X线片、CT和磁共振成像（MRI）所示的椎间盘间隙变窄、相邻椎体终板破坏、椎体硬化以及软组织肿胀。三人都有背痛；其中一人在活检时无症状。两例活检材料培养出金黄色葡萄球菌，一例培养出B组沙门氏菌。如果血培养为阴性，建议对椎体进行活检，以确定病变的活动情况、病原体类型及其对抗生素的敏感性。CT引导下的经皮活检是开放性手术活检的一种替代方法。
