基于显微断层扫描技术的陶瓷生物材料孔隙立体学分析

Ceramic Biomaterial Pores Stereology Analysis by the Use of Microtomography.

作者信息

Garczyk Żaneta, Jaegermann Zbigniew, Duda Piotr, Swinarew Andrzej S, Stach Sebastian

机构信息

Institute of Biomedical Engineering, Faculty of Science and Technology, University of Silesia in Katowice, Będzińska 39, 41-205 Sosnowiec, Poland.

Łukasiewicz Research Network, Ceramic and Concrete Division, Institute of Ceramics and Building Materials, Cementowa 8, 31-983 Kraków, Poland.

出版信息

Materials (Basel). 2021 Apr 25;14(9):2207. doi: 10.3390/ma14092207.

DOI:10.3390/ma14092207

PMID:33923089

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8123274/

Abstract

The main aim of this study was to analyze microtomographic data to determine the geometric dimensions of a ceramic porous material's internal structure. Samples of a porous corundum biomaterial were the research material. The samples were prepared by chemical foaming and were measured using an X-ray scanner. In the next stage, 3D images of the samples were generated and analyzed using Thermo Scientific Avizo software. The analysis enabled the isolation of individual pores. Then, the parameters characterizing the pore geometry and the porosity of the samples were calculated. The last part of the research consisted of verifying the developed method by comparing the obtained results with the parameters obtained from the microscopic examinations of the biomaterial. The comparison of the results confirmed the correctness of the developed method. The developed methodology can be used to analyze biomaterial samples to assess the geometric dimensions of biomaterial pores.

摘要

本研究的主要目的是分析显微断层扫描数据，以确定陶瓷多孔材料内部结构的几何尺寸。多孔刚玉生物材料的样本作为研究材料。样本通过化学发泡制备，并使用X射线扫描仪进行测量。在下一阶段，使用Thermo Scientific Avizo软件生成并分析样本的3D图像。该分析能够分离出单个孔隙。然后，计算表征样本孔隙几何形状和孔隙率的参数。研究的最后一部分包括通过将所得结果与生物材料微观检查获得的参数进行比较，来验证所开发的方法。结果比较证实了所开发方法的正确性。所开发的方法可用于分析生物材料样本，以评估生物材料孔隙的几何尺寸。