University of California, Irvine, Departments of Neurology & Neurological Surgery, 200 S. Manchester Avenue, Suite 206, Orange, CA 92686 USA.
J Stroke Cerebrovasc Dis. 2021 Sep;30(9):105819. doi: 10.1016/j.jstrokecerebrovasdis.2021.105819. Epub 2021 Apr 26.
Patients with renal disease have increased rates of admission to the neurological intensive care unit related to overlapping risk factors for renal and cerebrovascular disease as well as unique risks associated with renal dysfunction alone. Management of acute neurological injury in these patients requires individualized attention to diagnostic and management factors as they relate to coagulopathy, disorders of immune function, encephalopathy and renal replacement modalities. Careful consideration of these brain-kidney interactions is necessary to optimize care for this special patient population and improve neurological and renal outcomes.
患有肾脏疾病的患者因肾脏和脑血管疾病的重叠风险因素以及与肾功能不全相关的独特风险因素而增加了入住神经重症监护病房的几率。这些患者急性神经损伤的管理需要个体化关注与凝血障碍、免疫功能障碍、脑病和肾脏替代模式相关的诊断和管理因素。需要仔细考虑这些脑-肾相互作用,以优化对这一特殊患者群体的护理,改善神经和肾脏预后。