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急性乙型肝炎和慢性肝炎中特异性和非特异性免疫复合物的演变研究。

A study of the evolution of specific and non-specific immune complexes in acute hepatitis B and chronic hepatitis.

作者信息

Leyva A, Bernal M C, Piedrola G, Maroto M C

机构信息

Department of Microbiology, School of Medicine, Granada, Spain.

出版信息

J Med Microbiol. 1988 Jul;26(3):237-9. doi: 10.1099/00222615-26-3-237.

Abstract

Circulating immune complexes (ICs) containing IgG and HBsAg, and IgG and HBeAg, in sera from groups of patients with various liver diseases were sought by ELISA and immunodiffusion. A correlation was found between the absence of ICs and the disappearance of HBsAg in patients who had recovered from acute hepatitis B, but complexes containing HBsAg were always found in chronic hepatitis.

摘要

通过酶联免疫吸附测定法(ELISA)和免疫扩散法,在患有各种肝脏疾病的患者组血清中寻找含有IgG和乙肝表面抗原(HBsAg)以及IgG和乙肝e抗原(HBeAg)的循环免疫复合物(ICs)。在从急性乙型肝炎康复的患者中,发现ICs的缺失与HBsAg的消失之间存在相关性,但在慢性肝炎患者中总是能发现含有HBsAg的复合物。

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