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现有的危机护理标准分诊方案可能无法显著区分需要重症监护的2019冠状病毒病患者。

Existing Crisis Standards of Care Triage Protocols May Not Significantly Differentiate Between Patients With Coronavirus Disease 2019 Who Require Intensive Care.

作者信息

Rubin Emily B, Knipe Rachel S, Israel Rebecca A, McCoy Thomas H, Courtwright Andrew M

机构信息

Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA.

Center for Quantitative Health, Massachusetts General Hospital, Boston, MA.

出版信息

Crit Care Explor. 2021 Apr 26;3(4):e0412. doi: 10.1097/CCE.0000000000000412. eCollection 2021 Apr.

DOI:10.1097/CCE.0000000000000412
PMID:33928259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8078457/
Abstract

OBJECTIVES

To determine how several existing crisis standards of care triage protocols would have distinguished between patients with coronavirus disease 2019 requiring intensive care.

DESIGN

Retrospective cohort study.

SETTING

Single urban academic medical center.

PATIENTS

One-hundred twenty patients with coronavirus disease 2019 who required intensive care and mechanical ventilation.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

The characteristics of each patient at the time of ICU triage were used to determine how patients would have been prioritized using four crisis standards of care protocols. The vast majority of patients in the cohort would have been in the highest priority group using a triage protocol focusing on Sequential Organ Failure Assessment alone. Prioritization based on Sequential Organ Failure Assessment and 1-year life expectancy would have resulted in only slightly more differentiation between patients. Prioritization based on Sequential Organ Failure Assessment and 5-year life expectancy would have added significant additional differentiation depending on how priority groups were defined.

CONCLUSIONS

There is considerable controversy regarding the use of criteria other than prognosis for short-term survival in initial allocation of critical care resources under crisis standards of care triage protocols. To the extent that initial triage protocols would not create sufficient differentiation between patients, effectively resulting in a first-come, first-served initial allocation of resources, it is important to focus on how resources would be reallocated in the event of ongoing scarcity.

摘要

目的

确定几种现有的危机标准护理分诊方案如何区分需要重症监护的2019冠状病毒病患者。

设计

回顾性队列研究。

地点

单一城市学术医疗中心。

患者

120例需要重症监护和机械通气的2019冠状病毒病患者。

干预措施

无。

测量指标和主要结果

在重症监护病房分诊时,根据每位患者的特征,确定使用四种危机标准护理方案时患者的优先顺序。仅使用侧重于序贯器官衰竭评估的分诊方案,队列中的绝大多数患者会被列为最高优先级组。基于序贯器官衰竭评估和1年预期寿命进行优先级划分,患者之间的差异只会略有增加。基于序贯器官衰竭评估和5年预期寿命进行优先级划分,根据优先级组的定义方式,会增加显著的额外差异。

结论

在危机标准护理分诊方案下,在初始分配重症护理资源时,使用除短期生存预后以外的标准存在相当大的争议。如果初始分诊方案不能在患者之间产生足够的差异,实际上导致资源按先来先得的方式进行初始分配,那么关注在持续资源短缺情况下如何重新分配资源就很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b068/8078457/d0430bab64cc/cc9-3-e0412-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b068/8078457/9dbc3204db48/cc9-3-e0412-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b068/8078457/d0430bab64cc/cc9-3-e0412-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b068/8078457/9dbc3204db48/cc9-3-e0412-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b068/8078457/d0430bab64cc/cc9-3-e0412-g002.jpg

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本文引用的文献

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JAMA. 2021 Apr 13;325(14):1469-1470. doi: 10.1001/jama.2021.1545.
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Comparison of 2 Triage Scoring Guidelines for Allocation of Mechanical Ventilators.两种机械通气患者分诊评分指南的比较。
JAMA Netw Open. 2020 Dec 1;3(12):e2029250. doi: 10.1001/jamanetworkopen.2020.29250.
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Variation in Ventilator Allocation Guidelines by US State During the Coronavirus Disease 2019 Pandemic: A Systematic Review.
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Inequity in Crisis Standards of Care.危机护理标准中的不公平现象。
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