Zhemaĭtite D I, Varonetskas G A, Brozhaĭtene Iu I, Zhiliukas G A
Kardiologiia. 1988 Apr;28(4):35-41.
Vegetative control of the heart was assessed on the basis of cardiac rhythm (CR) and stroke volume parameters in the course of an active orthostatic test and bicycle ergometry in 508 myocardial infarction patients and 30 normal subjects. Central hemodynamic parameters and CR spectrum were examined with respect to phases of sleep in 125 coronary patients and 25 normal subjects. Coronary patients showed a disrupted vegetative CR regulation, which was chiefly parasympathetic (reduced CR response to an active orthostatic position and rationed exercise, and a smaller share of high-frequency constituent of the CR energy spectrum). Disrupted vegetative CR regulation was correlated with low hemodynamic baseline and respective values in active orthostatic position, exercise and REM sleep. Reduced CR response to stress as well as reduced CR spectrum during sleep corresponded to more severe clinical conditions.
在508例心肌梗死患者和30名正常受试者进行主动直立试验和自行车测力计运动过程中，根据心律（CR）和每搏输出量参数评估心脏的自主控制。在125例冠心病患者和25名正常受试者中，研究了睡眠各阶段的中心血流动力学参数和CR频谱。冠心病患者表现出自主CR调节紊乱，主要是副交感神经调节紊乱（对主动直立位和定量运动的CR反应降低，以及CR能谱高频成分的比例较小）。自主CR调节紊乱与低血流动力学基线以及主动直立位、运动和快速眼动睡眠时的相应值相关。对压力的CR反应降低以及睡眠期间CR频谱降低与更严重的临床状况相对应。
