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慢性原发性入睡期失眠的昆达里尼瑜伽治疗:与主动睡眠卫生比较的随机对照试验。

Treatment of chronic primary sleep onset insomnia with Kundalini yoga: a randomized controlled trial with active sleep hygiene comparison.

机构信息

Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts.

出版信息

J Clin Sleep Med. 2021 Sep 1;17(9):1841-1852. doi: 10.5664/jcsm.9320.

DOI:10.5664/jcsm.9320
PMID:33928908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8636338/
Abstract

STUDY OBJECTIVES

Prior studies have suggested a benefit of yoga for alleviating sleep disturbance; however, many studies have had methodological limitations. This trial study aimed to extend that literature by including an active sleep hygiene comparison.

METHODS

Participants aged 25-59 years with a primary complaint of sleep onset insomnia lasting at least 6 months were block randomized to an 8-week Kundalini yoga or sleep hygiene intervention, both consisting of initial 60-minute instruction and weekly check-ins. Daily sleep diaries and questionnaires were collected at baseline, throughout the intervention, and at 6-month follow-up. Data were analyzed using linear mixed models (n = 20 in each group).

RESULTS

Participant ratings of the interventions did not significantly differ. Sleep hygiene improved several diary and questionnaire outcomes, however, yoga resulted in even greater improvements corresponding to medium-to-large between-group effect sizes. Total sleep time increased progressively across yoga treatment ( = 0.95, = .002), concurrent with increased sleep efficiency ( = 1.36, < .001) and decreased sleep onset latency ( = -1.16, < .001), but without changes in pre-sleep arousal ( =-0.30, = .59). Remission rates were also higher for yoga compared to sleep hygiene, with ≥ 80% of yoga participants reporting average sleep onset latency < 30 minutes and sleep efficiency > 80% at 6-month follow-up. For over 50% of yoga participants, the insomnia severity index decreased by at least 8 points at end of treatment and follow-up.

CONCLUSIONS

Yoga, taught in a self-care framework with minimal instructor burden, was associated with self-reported improvements above and beyond an active sleep hygiene comparison, sustained at 6-month follow-up. Follow-up studies are needed to assess actigraphy and polysomnography outcomes, as well as possible mechanisms of change.

CLINICAL TRIAL REGISTRATION

Registry: ClinicalTrials.gov; Name: Yoga as a Treatment for Insomnia; URL: https://clinicaltrials.gov/ct2/show/NCT00033865; Identifier: NCT00033865.

CITATION

Khalsa SBS, Goldstein MR. Treatment of chronic primary sleep onset insomnia with Kundalini yoga: a randomized controlled trial with active sleep hygiene comparison. . 2021;17(9):1841-1852.

摘要

研究目的

先前的研究表明瑜伽有益于缓解睡眠障碍;然而,许多研究都存在方法学上的局限性。本试验研究旨在通过纳入主动睡眠卫生对照来扩展这一文献。

方法

参与者年龄在 25-59 岁之间,主要抱怨入睡困难,持续至少 6 个月,采用块随机分组,分别接受 8 周的昆达利尼瑜伽或睡眠卫生干预,均包括最初的 60 分钟指导和每周检查。在基线、干预期间和 6 个月随访时收集每日睡眠日记和问卷。使用线性混合模型(每组 20 名参与者)进行数据分析。

结果

参与者对干预的评价没有显著差异。睡眠卫生改善了几项日记和问卷结果,但瑜伽的效果更好,对应于中到大的组间效应大小。随着瑜伽治疗的进展,总睡眠时间逐渐增加(=0.95,=0.002),同时睡眠效率增加(=1.36,<0.001),入睡潜伏期缩短(=−1.16,<0.001),但睡前觉醒没有变化(=−0.30,=0.59)。与睡眠卫生相比,瑜伽的缓解率也更高,6 个月随访时,≥80%的瑜伽参与者报告平均入睡潜伏期<30 分钟,睡眠效率>80%。对于超过 50%的瑜伽参与者,在治疗结束和随访时,失眠严重程度指数至少下降了 8 分。

结论

在最小的指导负担下,以自我保健为框架教授的瑜伽与积极的睡眠卫生对照相比,与自我报告的改善相关,在 6 个月随访时仍可持续。需要进一步的研究来评估活动记录仪和多导睡眠图的结果,以及可能的变化机制。

临床试验注册

注册处:ClinicalTrials.gov;名称:瑜伽治疗失眠;网址:https://clinicaltrials.gov/ct2/show/NCT00033865;标识符:NCT00033865。

引文

Khalsa SBS,Goldstein MR。昆达利尼瑜伽治疗慢性原发性入睡困难:一项与主动睡眠卫生对照的随机对照试验。睡眠 2021;17(9):1841-1852。

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