Aguiar J L, Garzon F T, Schneider S, Berger M R, Schlag P, Schmähl D
Department of Surgery, Heidelberg University Im Neuenheimer Feld 110, FRG.
Lab Anim. 1988 Apr;22(2):173-6. doi: 10.1258/002367788780864510.
A technique for long-term infusion into the inferior mesenteric artery was developed which allows simple and reliable regional infusion into the colorectal segment of unrestrained rats. The cannulation system consists of an injection port 'In Stoppers' as a flow swivel, connected to an injection needle, which is inserted into a polyethylene tube protected by a steel spiral. During infusion the animals are free to move in the cage with access to food and water ad libitum. The method is suitable for regional chemotherapy as well as for studies of colorectal tumours in rats. In this study 73% of the cannulae remained functional for continuous infusion over a 15 day period.
开发了一种用于长期注入肠系膜下动脉的技术，该技术可对不受限制的大鼠结肠直肠段进行简单且可靠的局部注入。插管系统由作为流量旋转接头的注射端口“In Stoppers”组成，该端口连接到一根注射针，注射针插入由钢螺旋保护的聚乙烯管中。在注入过程中，动物可以在笼子里自由活动，随意获取食物和水。该方法适用于局部化疗以及大鼠结肠直肠肿瘤的研究。在本研究中，73%的插管在15天的时间内保持功能正常以进行持续注入。
