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非创伤性晶状体异位的儿童和青年晶状体手术后视网膜脱离的发生率。

Incidence of retinal detachment after lens surgery in children and young adults with nontraumatic ectopia lentis.

机构信息

From the Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, California (Heo, Lambert); Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju, South Korea (Heo).

出版信息

J Cataract Refract Surg. 2021 Nov 1;47(11):1454-1459. doi: 10.1097/j.jcrs.0000000000000667.

Abstract

PURPOSE

To determine the incidence of retinal detachment after lens surgery in children and young adults with nontraumatic ectopia lentis.

SETTING

Population-based claims data.

DESIGN

Population-based retrospective cohort study.

METHODS

Patients with nontraumatic ectopia lentis aged 30 years or younger who had undergone lens surgery with or without intraocular lens (IOL) implantation and had 1 year or greater continuous enrollment after lens surgery were included in the Optum deidentified Clinformatics Data Mart Database (2003 to 2019) and IBM MarketScan Databases (2007 to 2016). Both databases were assessed for sex, age, etiology of ectopia lentis, IOL implantation, and postoperative retinal detachment separately. Univariate and multivariate analyses were conducted to identify the risk factors for postoperative retinal detachment.

RESULTS

Among a total of 298 eyes (210 patients), IOL implantation was coupled with lens surgery in 151 eyes (49.8%) that underwent lens surgery for nontraumatic ectopia lentis. The median follow-up was 32 months in aphakic eyes and 29 months in pseudophakic eyes. Patients undergoing IOL implantation were older at the time of lens surgery (median age: no IOL, 6 years; IOL, 16 years; P < .001). Retinal detachment developed in 13 patients (14 eyes [4.7%]) 14 eyes (4.7%). Older age was the baseline characteristic that correlated most closely with the risk for retinal detachment (P = .05).

CONCLUSIONS

The rate of retinal detachment was similar with or without IOL implantation after lens surgery for nontraumatic ectopia lentis in children and young adults.

摘要

目的

确定非创伤性晶状体异位儿童和年轻患者晶状体手术后视网膜脱离的发生率。

背景

基于人群的理赔数据。

设计

基于人群的回顾性队列研究。

方法

将在 30 岁或以下患有非创伤性晶状体异位且行晶状体手术(伴或不伴人工晶状体 [IOL] 植入)的患者纳入 Optum 去识别化 Clinformatics Data Mart 数据库(2003 年至 2019 年)和 IBM MarketScan 数据库(2007 年至 2016 年)。这两个数据库都分别评估了性别、年龄、晶状体异位的病因、IOL 植入和术后视网膜脱离的情况。采用单变量和多变量分析来确定术后视网膜脱离的危险因素。

结果

在总共 298 只眼(210 例患者)中,151 只眼(49.8%)行晶状体手术治疗非创伤性晶状体异位时联合进行了 IOL 植入。无晶状体眼的中位随访时间为 32 个月,人工晶状体眼的中位随访时间为 29 个月。行 IOL 植入的患者在晶状体手术时年龄较大(无晶状体眼的中位年龄:6 岁;IOL 眼:16 岁;P <.001)。13 例患者(14 只眼 [4.7%])发生视网膜脱离。年龄较大是与视网膜脱离风险最密切相关的基线特征(P =.05)。

结论

在儿童和年轻患者非创伤性晶状体异位晶状体手术后,无论是否植入 IOL,视网膜脱离的发生率相似。

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