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用于犬类药物递送研究的改良型肠套管

Improved intestinal cannula for drug delivery studies in the dog.

作者信息

Rubinstein A, Li V H, Gruber P, Bass P, Robinson J R

机构信息

School of Pharmacy, University of Wisconsin, Madison 53706.

出版信息

J Pharmacol Methods. 1988 May;19(3):213-7. doi: 10.1016/0160-5402(88)90023-x.

Abstract

A modified light-weight intestinal cannula, based on the modified Thomas type (Thomas, 1941; Jones et al., 1971) was fabricated and tested. The design extends the useful life of the cannula and expands the versatility of the canine gastrointestinal (GI) system for pharmaceutical and physiological research. The cannula permits easy administration of pharmaceutical dosage forms directly into or access to ingested substances anywhere along the small intestine.

摘要

基于改良的托马斯型(托马斯,1941年;琼斯等人,1971年)制作并测试了一种改良的轻型肠插管。该设计延长了插管的使用寿命,并扩展了犬类胃肠(GI)系统在药物和生理学研究中的通用性。该插管允许将药物剂型直接轻松地施用于小肠内的任何位置或获取小肠内摄入的物质。

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