Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Oper Neurosurg (Hagerstown). 2021 Jul 15;21(2):E97-E98. doi: 10.1093/ons/opab128.
Some skull base tumors can be extremely hypervascular, incorporating multiple vascular territories and demonstrating arteriovenous shunting. Devascularization is a critical step undertaken early in meningioma surgery, necessary before the debulking that is required in skull base tumors. While devascularization can often be achieved with appropriate approach selection, bony drilling, and microsurgical cautery, preoperative embolization of meningiomas has an invaluable role in selected cases.1,2 Embolization, however, does have added risk, magnified in large tumors by the potential infarction with subsequent edema that can potentially lead to acute deterioration and neurosurgical emergency. Hence, to achieve devascularization of an extremely vascular tumor, embolization and surgical resection should be performed concomitantly, as one operation, in which embolization might be the first stage, or might be performed after the craniotomy flap is raised, if necessary.3 Naturally, this requires the multifaceted neurosurgical expertise of embolization and microsurgical resection, and the facility to perform such. We present a case of a giant, hypervascular, radiation-induced, skull base meningioma with internal and external carotid artery supply in a young patient with deteriorating vision in his only eye. Selective embolization of the internal maxillary, middle meningeal, and middle cerebral artery blood supplies was performed. Microsurgical interruption of the ethmoidal artery blood supply was then performed. This hybrid approach safely and effectively devascularized the tumor and allowed for a complete resection of this high-risk tumor4 while minimizing risk to the ophthalmic artery and optic nerve. The patient was consented for surgery.
一些颅底肿瘤可能极其富血管,合并多个血管区域,并表现出动静脉分流。血管化是脑膜瘤手术中早期进行的关键步骤,在颅底肿瘤需要进行减瘤之前是必要的。虽然通过适当的入路选择、骨钻和显微手术电凝可以实现血管化,但在某些情况下,脑膜瘤的术前栓塞具有不可估量的作用。1,2 栓塞有增加的风险,在大型肿瘤中,潜在的梗塞和随后的水肿可能导致急性恶化和神经外科急症,风险会放大。因此,为了实现极度富血管肿瘤的血管化,栓塞和手术切除应同时进行,作为一个操作,栓塞可以作为第一阶段,或者在开颅皮瓣抬起后进行,如果需要的话。3 自然,这需要栓塞和显微切除的多方面神经外科专业知识,以及执行这些操作的能力。我们介绍了一例年轻患者的巨大、富血管、放射性颅底脑膜瘤,该患者只有一只眼睛视力下降,肿瘤由颈内动脉和颈外动脉供血。对颌内动脉、脑膜中动脉和大脑中动脉的血液供应进行了选择性栓塞。然后对筛前动脉的血液供应进行了显微中断。这种混合方法安全有效地使肿瘤血管化,并允许完全切除这种高风险肿瘤 4,同时最大限度地降低对眼动脉和视神经的风险。患者已同意手术。