Weinberg H, Pozez A
Department of Surgery, Mount Sinai School of Medicine, New York, NY 10029.
Microsurgery. 1988;9(1):24-8. doi: 10.1002/micr.1920090109.
Recently sodium fluorescein has been used to determine viability of tissue and assess blood flow. No study, however, has documented the correlation of surface fluorescence as measured by the dermatofluorometer with the actual distribution of fluorescein in tissue. Abdominal skin flaps were raised on Sprague-Dawley rats. Following intravenous injection of sodium fluorescein, skin surface fluorescence was measured and compared with tissue fluorescein concentration. This study confirms that skin surface fluorescence correlates well with actual fluorescein distribution in tissue. Furthermore, the study clearly illustrates the statistically significant variation of surface fluorescence as a function of distance from the vascular pedicle.
最近，荧光素钠已被用于确定组织的活力并评估血流情况。然而，尚无研究记录通过皮肤荧光计测量的表面荧光与荧光素在组织中的实际分布之间的相关性。在斯普拉格-道利大鼠身上掀起腹部皮瓣。静脉注射荧光素钠后，测量皮肤表面荧光并与组织荧光素浓度进行比较。本研究证实皮肤表面荧光与荧光素在组织中的实际分布密切相关。此外，该研究清楚地表明，表面荧光作为距血管蒂距离的函数存在统计学上的显著差异。
