一种来自……根部的新二芳基己烷和两种新二芳基丙醇。
A new diarylhexane and two new diarylpropanols from the roots of .
作者信息
Sriphana Uraiwan, Yenjai Chavi, Suthiwong Jittra, Poopasit Kitisak
机构信息
Department of Science and Technology, Faculty of Liberal Arts and Science, Roi Et Rajabhat University, Roi Et, Thailand.
Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Natural Products Research Unit, Khon Kaen University, Khon Kaen, Thailand.
出版信息
Nat Prod Res. 2022 Apr;36(7):1741-1748. doi: 10.1080/14786419.2020.1815736. Epub 2020 Sep 16.
A new diarylhexane, kneglobularone B () and two new diarylpropanols, kneglobularols A - B () along with seven known compounds () were isolated and characterized from the roots of It is the first time to find arylpropyl quinone () and isoflavone () in Myristicaceae family. In addition, was found for the first time in genus. Their structures were elucidated by UV, IR, MS, 1 D and 2 D NMR techniques. Compound exhibited strong cytotoxicity against the NCI - H187 and MCF - 7 cell lines with IC values of 3.08 and 6.68 µg/mL, respectively.
从的根部分离并鉴定出一种新的二芳基己烷、球形酮B（）和两种新的二芳基丙醇、球形醇A - B（）以及七种已知化合物（）。这是首次在肉豆蔻科植物中发现芳基丙基醌（）和异黄酮（）。此外，在属中首次发现了**。通过紫外、红外、质谱、一维和二维核磁共振技术对它们的结构进行了阐明。化合物**对NCI - H187和MCF - 7细胞系表现出强细胞毒性，IC值分别为3.08和6.68μg/mL。
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