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NAV2 positively modulates inflammatory response of fibroblast-like synoviocytes through activating Wnt/β-catenin signaling pathway in rheumatoid arthritis.

作者信息

Wang Ran, Li Meng, Wu Weijun, Qiu Yuanye, Hu Wei, Li Zhaoyi, Wang Zhou, Yu Yue, Liao Junyi, Sun Wuyi, Mao Jianchun, Zhu Yi Zhun

机构信息

State Key Laboratory of Quality Research in Chinese Medicine, School of Pharmacy, Macau University of Science and Technology, Macau, China.

Department of Pharmacology, Shanghai Key Laboratory of Bioactive Small Molecules, School of Pharmacy, Fudan University, Shanghai, China.

出版信息

Clin Transl Med. 2021 Apr;11(4):e376. doi: 10.1002/ctm2.376.

DOI:10.1002/ctm2.376
PMID:33931978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8087903/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8918/8087903/0b61ce702189/CTM2-11-e376-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8918/8087903/67cb68c27bb6/CTM2-11-e376-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8918/8087903/061d90e7fafe/CTM2-11-e376-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8918/8087903/0b61ce702189/CTM2-11-e376-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8918/8087903/67cb68c27bb6/CTM2-11-e376-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8918/8087903/061d90e7fafe/CTM2-11-e376-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8918/8087903/0b61ce702189/CTM2-11-e376-g002.jpg

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Pain. 2020 Sep 1;161(9):2129-2141. doi: 10.1097/j.pain.0000000000001890.
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NAV2 facilitates invasion of cutaneous melanoma cells by targeting SNAI2 through the GSK-3β/β-catenin pathway.NAV2 通过靶向 SNAI2 并激活 GSK-3β/β-catenin 通路促进皮肤黑色素瘤细胞的侵袭。
Arch Dermatol Res. 2019 Jul;311(5):399-410. doi: 10.1007/s00403-019-01909-w. Epub 2019 Apr 17.
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BMC Genomics. 2025 Aug 2;26(1):718. doi: 10.1186/s12864-025-11914-1.
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