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世卫组织医院抗生素使用现况调查方法学应当加以改进:来自墨西哥四家医院试点研究的经验教训。

The WHO methodology for point prevalence surveys on antibiotics use in hospitals should be improved: Lessons from pilot studies in four Mexican hospitals.

机构信息

Center for Infectious Diseases Research (CISEI), National Institute of Public Health (INSP), Universidad No. 655, Colonia Santa María Ahuacatitlán, C.P. 62100 Cuernavaca, Morelos, Mexico.

Center for Evaluation and Surveys Research (CIEE), National Institute of Public Health (INSP), Universidad No. 655, Colonia Santa María Ahuacatitlán, C.P. 62100 Cuernavaca, Morelos, Mexico.

出版信息

Int J Infect Dis. 2021 Jul;108:13-17. doi: 10.1016/j.ijid.2021.04.079. Epub 2021 Apr 28.

DOI:10.1016/j.ijid.2021.04.079
PMID:33932602
Abstract

Point prevalence surveys (PPSs) are a useful option for collecting antimicrobial prescription data in hospitals where regular monitoring is not feasible. The methodology recommended by the World Health Organization (WHO) for conducting PPSs (WPPS), which targets low- and middle-income countries (LMICs), attempts to respond to the lag in these regions to generate estimates for antimicrobial use. However, based on our experience in four third-level public hospitals in Mexico, we identified substantial gaps in the WPPS guide with regards to addressing common challenges for the implementation of PPSs. While the oversimplified narrative of WPPS could facilitate the adoption of this methodology and extend its use, it underestimates the efforts and potential pitfalls for survey preparation, coordination, and reliable implementation. Conducting rigorous pilot studies could reduce the WPPS deficiencies and strengthen the reliability and comparability of the estimates for antimicrobial use.

摘要

点 prevalence 调查(PPSs)是在定期监测不可行的医院中收集抗菌药物处方数据的有用选择。世界卫生组织(WHO)为进行 PPSs(WPPS)推荐的方法,针对低收入和中等收入国家(LMICs),试图应对这些地区的滞后,为抗菌药物使用生成估计值。然而,根据我们在墨西哥四家三级公立医院的经验,我们发现 WPPS 指南在解决 PPSs 实施的常见挑战方面存在很大差距。虽然 WPPS 过于简化的叙述可能会促进这种方法的采用并扩大其使用范围,但它低估了为调查准备、协调和可靠实施所做的努力和潜在陷阱。进行严格的试点研究可以减少 WPPS 的缺陷,并提高抗菌药物使用估计值的可靠性和可比性。

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