Department of Anaesthesiology and Intensive Care, Kuopio University Hospital, Puijonlaaksontie 2, PO Box 100, 70029, Kuopio, Finland.
School of Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
BMC Pulm Med. 2021 May 1;21(1):144. doi: 10.1186/s12890-021-01515-5.
Pulmonary diseases affect health-related quality of life (HRQoL), but there are few data on patients' adaptation to a serious illness. This study assessed resilience and its associations with HRQoL, life satisfaction, anxiety and depression in patients with pulmonary diseases receiving ambulatory oxygen therapy.
In this prospective cohort study, we enrolled 42 patients with pulmonary diseases receiving ambulatory oxygen therapy. The patients completed the following questionnaires at baseline and after one and three months; the Resilience Scale-25, the Life Satisfaction Scale-4, the 15D instrument of HRQoL, the Hospital Anxiety and Depression Scale (HADS) and the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST 2.0). To compare HRQoL, we recruited age- and gender-matched controls from the general population (n = 3574). The primary outcome was the proportion of patients with low resilience.
Half (42-48%) of the patients had low resilience, which was correlated with low HRQoL, low levels of life satisfaction and higher levels of anxiety and depression. Patients had very low HRQoL compared to controls. Dissatisfaction with life increased during the 3-months follow-up, but only a few patients had anxiety or depression. Patient satisfaction with assistive technology was high; the median QUEST 2.0 score (scale 1-5) was 4.00 at baseline, 3.92 at one month and 3.88 at three months.
Resilience was low in half of the patients with pulmonary diseases receiving ambulatory oxygen therapy. Higher resilience was positively correlated with HRQoL and life satisfaction and negatively correlated with anxiety and depression.
ClinicalTrials.gov Protocol Record 507A023. Registered 17 September 2020-Retrospectively registered, https://clinicaltrials.gov/ct2/results?cond=&term=NCT04554225&cntry=&state=&city=&dist= .
肺部疾病会影响健康相关生活质量（HRQoL），但关于患者对严重疾病的适应情况的数据很少。本研究评估了接受门诊氧疗的肺部疾病患者的适应力及其与 HRQoL、生活满意度、焦虑和抑郁的相关性。
在这项前瞻性队列研究中，我们纳入了 42 名接受门诊氧疗的肺部疾病患者。患者在基线时以及 1 个月和 3 个月后完成了以下问卷：弹性量表-25、生活满意度量表-4、15D 健康相关生活质量量表、医院焦虑和抑郁量表（HADS）以及魁北克用户对辅助技术满意度问卷（QUEST 2.0）。为了比较 HRQoL，我们从一般人群中招募了年龄和性别匹配的对照组（n=3574）。主要结局是低弹性患者的比例。
一半（42-48%）的患者弹性较低，与 HRQoL 较低、生活满意度较低以及焦虑和抑郁水平较高相关。与对照组相比，患者的 HRQoL 非常低。在 3 个月的随访期间，对生活的不满情绪增加，但只有少数患者有焦虑或抑郁。患者对辅助技术的满意度较高；基线时 QUEST 2.0 评分（量表 1-5）中位数为 4.00，1 个月时为 3.92，3 个月时为 3.88。
接受门诊氧疗的肺部疾病患者中，有一半的患者适应力较低。较高的适应力与 HRQoL 和生活满意度呈正相关，与焦虑和抑郁呈负相关。
ClinicalTrials.gov 方案记录 507A023。2020 年 9 月 17 日注册-回顾性注册，https://clinicaltrials.gov/ct2/results?cond=&term=NCT04554225&cntry=&state=&city=&dist=。
