Department of Biomedical Engineering, Lund University, Sweden.
Department of Biomedical Engineering, Lund University, Sweden.
J Biomech. 2021 Jun 9;122:110445. doi: 10.1016/j.jbiomech.2021.110445. Epub 2021 Apr 17.
Low impact falls to the side are the main cause of hip fractures in elderly. Finite element (FE) models of the proximal femur may help in the assessment of patients at high risk for a hip fracture. However, extensive validation is essential before these models can be used in a clinical setting. This study aims to use strain measurements from bilateral digital image correlation to validate an FE model against ex vivo experimental data of proximal femora under a sideways fall loading condition. For twelve subjects, full-field strain measurements were available on the medial and lateral side of the femoral neck. In this study, subject-specific FE models were generated based on a consolidated procedure previously validated for stance loading. The material description included strain rate dependency and separate yield and fracture strain limits in tension and compression. FE predicted fracture force and experimentally measured peak forces showed a strong correlation (R = 0.92). The FE simulations predicted the fracture initiation within 3 mm distance of the experimental fracture line for 8/12 subjects. The predicted and measured strains correlated well on both the medial side (R = 0.87) and the lateral side (R = 0.74). The lower correlation on the lateral side is attributed to the irregularity of the cortex and presence of vessel holes in this region. The combined validation against bilateral full-field strain measurements and peak forces has opened the door for a more elaborate qualitative and quantitative validation of FE models of femora under sideways fall loading.
向侧面的低撞击力是导致老年人髋部骨折的主要原因。股骨近端的有限元(FE)模型有助于评估高髋部骨折风险的患者。然而,在这些模型可用于临床环境之前,必须进行广泛的验证。本研究旨在使用双侧数字图像相关的应变测量值来验证 FE 模型,以对抗侧向跌倒加载条件下的股骨近端离体实验数据。对于 12 名受试者,股骨颈的内侧和外侧均有全场应变测量值。在这项研究中,基于以前针对站立负荷验证的综合程序生成了特定于受试者的 FE 模型。材料描述包括应变率依赖性以及拉伸和压缩中单独的屈服和断裂应变极限。FE 预测的骨折力与实验测量的峰值力之间存在很强的相关性(R = 0.92)。FE 模拟预测 8/12 名受试者中有 8 名在实验骨折线 3 毫米范围内发生骨折起始。在内部(R = 0.87)和外部(R = 0.74),预测和测量的应变都很好地相关。在外部相关性较低归因于该区域皮质的不规则性和血管孔的存在。通过双侧全场应变测量值和峰值力的综合验证,为侧向跌倒加载下股骨的 FE 模型进行更精细的定性和定量验证开辟了道路。