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先天性脑肿瘤的自发消退:两例报告。

Spontaneous regression of congenital brain tumors: a report of two cases.

机构信息

Department of Pediatric Neurosurgery, Children's Medical Center Hospital, Tehran University of Medical Sciences, Tehran, 1419733151, Iran.

出版信息

Childs Nerv Syst. 2021 Dec;37(12):3901-3905. doi: 10.1007/s00381-021-05172-1. Epub 2021 May 1.

DOI:10.1007/s00381-021-05172-1
PMID:33934203
Abstract

BACKGROUND

Vanishing brain tumor is defined as spontaneously disappearing or decreasing of the initial brain mass volume to ≤ 70% before establishing the definitive diagnosis. The condition is rare and can be attributed to different factors. The exact mechanism is under debate, but the increasing rate and accuracy of neuroimaging studies and occurrence of similar scenario in other pathologies rather than brain tumors can be of particular importance in finding vanishing brain lesions.

CASE REPORT

We present two unusual cases of congenital brain masses which underwent spontaneous shrinkage within the first months of life.

CONCLUSION

The condition is scarcely observed in congenital brain masses. As congenital brain lesions are distinct entities with peculiar characteristics, this rare phenomenon may reflect different aspects in this age group.

摘要

背景

消失性脑瘤是指在明确诊断前,初始脑质量体积自发消失或减少至≤70%。这种情况很少见,可能归因于不同的因素。确切的机制仍存在争议,但神经影像学研究的发生率和准确性不断提高,以及在其他病变而不是脑瘤中出现类似情况,对于发现消失性脑病变具有特别重要的意义。

病例报告

我们介绍了两个不寻常的先天性脑肿块病例,它们在生命的头几个月内自发缩小。

结论

这种情况在先天性脑肿块中很少见。由于先天性脑病变是具有特殊特征的独特实体,这种罕见现象可能反映了该年龄组的不同方面。

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本文引用的文献

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Burned-Out Testicular Cancer: Really a Different History?消退型睾丸癌:真的有不同的病史吗?
Case Rep Oncol. 2017 Sep 20;10(3):846-850. doi: 10.1159/000480493. eCollection 2017 Sep-Dec.
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Ghost Tumors of the Central Nervous System: Definition, Clinical Implications, and Proposal of Classification.中枢神经系统的幽灵瘤:定义、临床意义及分类建议
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Long-term follow-up of vanishing tumors in the brain: how should a lesion mimicking primary CNS lymphoma be managed?脑内消失性肿瘤的长期随访:类似原发性中枢神经系统淋巴瘤的病变应如何处理?
Clin Neurol Neurosurg. 2012 Nov;114(9):1217-21. doi: 10.1016/j.clineuro.2012.02.053. Epub 2012 Mar 22.
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Identification of disappearing brain lesions with intraoperative magnetic resonance imaging prevents surgery.术中磁共振成像识别消失的脑病变可避免手术。
Neurosurgery. 2010 Oct;67(4):1061-5; discussion 1065. doi: 10.1227/NEU.0b013e3181ee4303.
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Neurosurg Focus. 2006 Nov 15;21(5):E3. doi: 10.3171/foc.2006.21.5.4.
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Tectal plate lesions in children.儿童顶盖板病变
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Inflammatory demyelinating disease mimicking malignant glioma.
J Nucl Med. 2003 Apr;44(4):565-9.
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Is a "vanishing tumor" always a lymphoma?“消失的肿瘤”就一定是淋巴瘤吗?
Neurology. 2002 Sep 10;59(5):762-4. doi: 10.1212/wnl.59.5.762.
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