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自体耳甲软骨移植治疗声带瘢痕及声带沟。

Autologous Tragal Perichondrium Graft for Vocal Fold Scar and Sulcus Vocalis.

机构信息

Department of Otorhinolaryngology, University Hospital Donostia-San Sebastián, Spain.

Department of Otorhinolaryngology, University Hospital Donostia-San Sebastián, Spain.

出版信息

J Voice. 2022 Sep;36(5):701-706. doi: 10.1016/j.jvoice.2020.08.024. Epub 2021 Apr 30.

DOI:10.1016/j.jvoice.2020.08.024
PMID:33934935
Abstract

Between 2006 and 2016 in a Tertiary Academic Center, 11 patients underwent phonomicrosurgery with tragal perichondrium graft placement in Reinke's space for the treatment of sulcus (Ford type 2) and vocal fold scar. A total of six patients out of 11 had an additional autologous fat implantation in order to improve the glottic closure. We evaluated the functional outcome using the Spanish validated version of the VHI- 30 before and 6 months after the surgery. We also measured the subjective appreciation of the obtained outcome, a perceptual voice evaluation using GRBAS scale, and changes in videostroboscopy examinations concerning mucosal wave and glottic closure. In the VHI-30 questionnaire, we observed an improvement in all patients (six of which showed an improvement of 50% or more) with statistically significant results (P = 0.003), and no significant differences between sulcus (Ford type 2) and vocal cord scar patients (P = 0.7579). The results obtained from the single question assessing changes in voice quality showed a high improvement in seven patients. According to the GRBAS scale, all cases improved. Concerning the results of the videostroboscopy, two patients obtained very favorable results, eight of them presented a moderate recovery and only one improved slightly. The following complications were identified: two granulomas, a graft extrusion and a tragal infection. The tragal perichondrium used as an autograft in Reinke's space appears to be a safe and satisfactory choice, comparable to other grafts such as temporalis fascia or autologous fat.

摘要

在 2006 年至 2016 年期间,在一家三级学术中心,有 11 名患者接受了鼓膜软骨移植植入雷尼克氏间隙的声门微创手术,用于治疗沟(福特 2 型)和声带瘢痕。为了改善声门闭合,共有 11 名患者中的 6 名进行了额外的自体脂肪移植。我们使用西班牙语验证版 VHI-30 在手术前后 6 个月评估了功能结果。我们还测量了获得的结果的主观评价,使用 GRBAS 量表进行感知声音评估,以及视频频闪喉镜检查中关于黏膜波和声门闭合的变化。在 VHI-30 问卷中,我们观察到所有患者(其中 6 名患者的改善幅度超过 50%)均有改善,结果具有统计学意义(P=0.003),且沟(福特 2 型)和声带瘢痕患者之间无显著差异(P=0.7579)。评估声音质量变化的单一问题的结果显示,有 7 名患者的声音有了很大的改善。根据 GRBAS 量表,所有病例均有改善。关于频闪喉镜的结果,有 2 名患者的结果非常好,8 名患者的恢复情况中等,只有 1 名患者略有改善。确定了以下并发症:2 个肉芽肿、1 个移植物脱出和 1 个鼓膜炎。鼓膜软骨作为 Reinke 间隙的自体移植物似乎是一种安全且令人满意的选择,可与颞筋膜或自体脂肪等其他移植物相媲美。

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