Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.
Obstetrix Medical Group of Colorado, Denver, CO, USA.
J Neonatal Perinatal Med. 2022;15(1):195-202. doi: 10.3233/NPM-200667.
Venous varicosities are a relatively common finding during pregnancy. Rarely, varices can arise in the cervix and cause life-threatening maternal hemorrhage. This article offers an example of a patient who was diagnosed with bleeding cervical varices during pregnancy and summarizes the diagnosis and treatment strategies for the 20 other reported cases in the literature.
A PubMed literature search using the following terms was performed to gather data for the literature review: "bleeding" or "hemorrhage" and "cervical varices" or "cervical varix" or "cervical varicosities" and "pregnancy" or "obstetric" or "maternal." Individual references cited in each article were also evaluated for inclusion in this review.
A 50-year-old gravida 7 para 1 presented at 12 4/7 weeks with vaginal bleeding. Endo-vaginal ultrasound showed enhanced color Doppler signal in the endocervical canal. During a speculum exam, she was found to have active bleeding from ruptured cervical varicosities and required blood and fresh frozen plasma transfusion. Hemostasis was achieved with interrupted suture ligation. A McDonald cerclage was subsequently placed. She continued pregnant until delivery via cesarean section at 37 2/7 weeks. To date, there have only been 20 other reported cases of bleeding cervical varices during pregnancy.
This case report and review of the literature highlight the importance of including bleeding cervical varices in the differential diagnosis of maternal hemorrhage and offer a treatment strategy if cervical varicosities are discovered during pregnancy.
静脉静脉曲张在妊娠期间较为常见。但极罕见情况下,宫颈也可能出现静脉曲张并导致危及生命的产妇出血。本文提供了一例妊娠期间诊断为宫颈静脉曲张出血的患者,并对文献中报道的 20 例其他病例的诊断和治疗策略进行了总结。
通过 PubMed 文献检索,使用以下术语收集文献综述的数据:“出血”或“ hemorrhage”和“宫颈静脉曲张”或“宫颈静脉瘤”或“宫颈静脉曲张”和“妊娠”或“产科”或“产妇”。还评估了每篇文章中引用的参考文献是否包含在本综述中。
一位 50 岁的 7 次妊娠 1 次分娩的患者在 12 周 4/7 天出现阴道出血。经阴道超声显示宫颈管内增强彩色多普勒信号。在阴道镜检查中,发现她有破裂的宫颈静脉曲张出血,需要输血和新鲜冷冻血浆。通过间断缝合结扎止血。随后放置了 McDonald 宫颈环扎术。她继续妊娠,直至 37 周 2/7 天通过剖宫产分娩。迄今为止,仅报道了 20 例其他妊娠期间宫颈静脉曲张出血的病例。
本病例报告和文献复习强调了在产妇出血的鉴别诊断中包括宫颈静脉曲张出血的重要性,并提供了如果在妊娠期间发现宫颈静脉曲张的治疗策略。