Pons T P, Garraghty P E, Mishkin M
Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, MD 20892.
Proc Natl Acad Sci U S A. 1988 Jul;85(14):5279-81. doi: 10.1073/pnas.85.14.5279.
We have reported that elimination of the representation of any body part in the primary (i.e., postcentral) somatosensory cortex of the adult macaque selectively eliminates the representation of that same body part in the second somatosensory area SII. We now report that, although removal of the entire postcentral hand representation does indeed leave the SII hand representation unresponsive to somatic stimulation initially, 6-8 weeks later this cortex is no longer silent. Instead, most or all of the region that had been vacated by the hand representation is now found to be occupied by an expanded foot representation. This massive somatotopic reorganization, involving more than half the areal extent of SII, exceeds that previously observed in the postcentral cortex after peripheral nerve damage and may reflect a greater capacity for reorganizational changes in higher order than in primary sensory cortical areas.
我们曾报道，在成年猕猴的初级（即中央后回）体感皮层中消除任何身体部位的表征，会选择性地消除第二体感区SII中同一身体部位的表征。我们现在报道，虽然移除整个中央后回手部表征确实会使SII手部表征最初对躯体刺激无反应，但6 - 8周后，该皮层不再沉默。相反，现在发现大部分或全部曾被手部表征 vacated 的区域被扩展的足部表征占据。这种大规模的躯体定位重组，涉及SII超过一半的面积范围，超过了先前在周围神经损伤后中央后回皮层中观察到的情况，可能反映出高阶区域比初级感觉皮层区域具有更大的重组变化能力。 （注：原文中 vacated 未查到确切释义，这里保留英文以便准确理解原文，你可根据实际情况进一步处理。）
