Strashilov Strahil Asenov, Nanev Vasil, Slavchev Stanislav, Ivanova Denislava, Kostov Stoyan, Yordanov Angel
Medical University of Pleven, Bulgaria.
Medical University Varna, Bulgaria.
Prz Menopauzalny. 2021 Apr;20(1):61-63. doi: 10.5114/pm.2021.104166. Epub 2021 Mar 5.
Radiotherapy (RT) is a widely used treatment modality of malignant tumours of the uterine cervix and body. There are different techniques to deliver RT to the tumour lesions, including external beam radiation and brachytherapy. All international guidelines recommend RT as treatment modality for many stages of uterine cervical and body cancers because it improves a number of oncological outcomes, such as disease-free and overall survival. However, it may also lead to a number of complications, which can be roughly divided into early or late, depending on the time of their manifestation. The most frequent RT-induced early complications involve the skin and the soft subcutaneous tissues. They typically present as inflammatory conditions of all abdominal wall layers: dermatitis, cellulitis, and necroses of subcutaneous fatty tissue, muscles, or fasciae.
This paper presents a case report of a 38-year-old woman diagnosed with endometrial cancer (EC). She was initially treated with open abdominal surgery, and subsequently the treatment was continued with external beam adjuvant RT.
While RT was ongoing, a necrosis of the anterior abdominal wall in the surgical scar developed. It manifested at the end of the RT treatment and is thus regarded as an early complication of the RT for EC. It was successfully managed with surgery, and there was no compromise in the treatment of the oncological condition.
RT-induced necrosis of the surgical scar of the anterior abdominal wall is a very rare complication. Surgical treatment is the main method of treatment of this condition.
放射治疗（RT）是子宫颈和子宫体恶性肿瘤广泛应用的治疗方式。有多种将放射治疗应用于肿瘤病灶的技术，包括外照射放疗和近距离放疗。所有国际指南都推荐放射治疗作为子宫颈癌和子宫体癌多个分期的治疗方式，因为它能改善多种肿瘤学结局，如无病生存期和总生存期。然而，它也可能导致多种并发症，根据其出现时间可大致分为早期或晚期。最常见的放疗引起的早期并发症累及皮肤和皮下软组织。它们通常表现为整个腹壁各层的炎症情况：皮炎、蜂窝织炎以及皮下脂肪组织、肌肉或筋膜的坏死。
本文呈现了一名38岁被诊断为子宫内膜癌（EC）的女性的病例报告。她最初接受了开腹手术治疗，随后继续接受外照射辅助放疗。
在放疗进行期间，手术瘢痕处的前腹壁发生了坏死。它在放疗结束时出现，因此被视为子宫内膜癌放疗的早期并发症。通过手术成功处理，肿瘤病情的治疗未受影响。
放疗引起的前腹壁手术瘢痕坏死是一种非常罕见的并发症。手术治疗是这种情况的主要治疗方法。
